/* Binder detail page — mirrors protein-detail design language with a denser
   chemistry-oriented layout (physchem, drug-likeness, provenance, siblings). */

.binder-page {
    font-family: "Source Sans 3", "Segoe UI", sans-serif;
    color: var(--tp-ink);
    margin: 0;
    display: grid;
    gap: var(--tp-space-4);
    --binder-accent: var(--tp-color-brand-800);
    --binder-accent-ink: var(--tp-color-brand-900);
    --binder-accent-soft: var(--tp-color-brand-100);
    --binder-accent-border: var(--tp-color-brand-300);
    --binder-pass: var(--tp-color-success-ink);
    --binder-pass-soft: var(--tp-color-success-bg);
    --binder-pass-border: var(--tp-color-success-border);
    --binder-fail: var(--tp-color-danger-ink);
    --binder-fail-soft: var(--tp-color-danger-bg);
    --binder-fail-border: var(--tp-color-danger-border);
    --binder-warn: var(--tp-color-warning-ink);
    --binder-warn-soft: var(--tp-color-warning-bg);
    --binder-warn-border: var(--tp-color-warning-border);
}

.binder-page h1,
.binder-page h2,
.binder-page h3 {
    font-family: "Space Grotesk", "Segoe UI", sans-serif;
    font-weight: 600;
    letter-spacing: 0.2px;
}
.binder-page h1 { font-weight: 700; }

.binder-page code {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.92em;
    background: var(--tp-color-surface-soft);
    padding: 1px 6px;
    border-radius: 4px;
    border: 1px solid var(--tp-color-border-soft);
    color: var(--tp-color-text-primary);
}

.binder-hero,
.binder-page .quick-nav,
.binder-card {
    animation: tp-ui-enter 340ms var(--tp-ui-ease-standard) both;
}

.binder-page .quick-nav {
    animation-delay: 40ms;
}

.binder-card {
    animation-delay: 80ms;
}

.binder-card:nth-of-type(2) { animation-delay: 110ms; }
.binder-card:nth-of-type(3) { animation-delay: 140ms; }
.binder-card:nth-of-type(4) { animation-delay: 170ms; }

/* ── Hero ─────────────────────────────────────────────────────────── */

/* Base styles from .tp-page-hero in ui-system.css */

.binder-hero-top {
    display: flex;
    justify-content: space-between;
    gap: 18px;
    align-items: flex-start;
    margin-top: 8px;
}

.binder-hero-content {
    max-width: none;
    width: 100%;
}

.binder-hero-eyebrow {
    margin: 6px 0 10px;
    color: var(--tp-color-text-muted);
    font-size: var(--tp-font-label);
    font-weight: 500;
    letter-spacing: 0.08em;
    text-transform: uppercase;
}

.binder-hero h1 {
    margin: 0;
    font-size: var(--tp-heading-lg);
    line-height: 1.1;
    color: var(--binder-accent-ink);
    word-break: break-all;
}

.binder-description {
    margin: 10px 0 0;
    color: var(--tp-color-text-secondary);
    font-size: 1rem;
    line-height: 1.42;
    max-width: 920px;
}

.binder-context {
    margin: 10px 0 0;
    color: var(--tp-color-text-secondary);
    font-size: 0.95rem;
}

.binder-context-id {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    color: var(--binder-accent-ink);
    font-weight: 600;
    text-decoration: none;
}

.binder-context-id:hover,
.binder-context-id:focus-visible {
    text-decoration: underline;
    outline: none;
}

.binder-context-desc {
    color: var(--tp-color-text-muted);
}

.binder-hero .hero-chip-list {
    margin-top: 12px;
}

.binder-pdb-chip {
    text-decoration: none !important;
    display: inline-flex;
    align-items: center;
    gap: 5px;
    transition: background 120ms ease, border-color 120ms ease;
}

.binder-pdb-chip:hover {
    border-color: var(--binder-accent-border) !important;
    background: var(--binder-accent-soft) !important;
}

.binder-ext-icon {
    width: 10px;
    height: 10px;
    flex-shrink: 0;
    color: var(--tp-color-text-muted);
}

.binder-formula-chip {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.8rem !important;
    letter-spacing: 0.01em;
}

/* ── Metric pills ─────────────────────────────────────────────────── */

.binder-metrics {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(160px, 1fr));
    gap: 10px;
    margin-top: 14px;
}

.binder-page .metric-pill {
    border: 1px solid var(--binder-accent-border);
    border-radius: 12px;
    background: var(--tp-color-surface);
    padding: 10px 14px;
    min-height: 68px;
    display: grid;
    align-content: center;
    gap: 3px;
}

.binder-page .metric-label {
    font-size: 0.73rem;
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.05em;
    color: var(--tp-color-text-muted);
}

.binder-page .metric-value {
    color: var(--binder-accent-ink);
    font-size: 1.15rem;
    line-height: 1.2;
    font-weight: 600;
}

.metric-unit {
    font-size: 0.78rem;
    font-weight: 500;
    color: var(--tp-color-text-muted);
}

.binder-page .metric-value--text {
    font-size: 0.96rem;
    word-break: break-all;
}

.binder-page .metric-value--ok {
    color: var(--binder-pass);
}

.binder-page .metric-value--warn {
    color: var(--binder-warn);
}

.binder-page .metric-value a {
    color: inherit;
    text-decoration: none;
}

.binder-page .metric-value a:hover,
.binder-page .metric-value a:focus-visible {
    text-decoration: underline;
    outline: none;
}

/* ── Quick-nav ────────────────────────────────────────────────────── */

.binder-page .quick-nav {
    position: sticky;
    top: -2px;
    z-index: 25;
    display: flex;
    flex-wrap: nowrap;
    gap: 8px;
    overflow-x: auto;
    padding: 8px 10px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 12px;
    background: var(--tp-color-surface-soft);
}

.binder-page .quick-nav::-webkit-scrollbar {
    height: 6px;
}

.binder-page .quick-nav::-webkit-scrollbar-thumb {
    background: var(--tp-color-border-strong);
    border-radius: 999px;
}

.binder-page .quick-nav .quick-nav-link {
    flex: 0 0 auto;
    display: inline-flex;
    align-items: center;
    justify-content: center;
    min-height: 36px;
    padding: 0.32rem 0.85rem;
    line-height: 1.1;
    font-weight: 500;
    border-radius: 999px;
    border: 1px solid var(--tp-color-border) !important;
    background: var(--tp-color-surface) !important;
    color: var(--tp-color-text-secondary) !important;
    white-space: nowrap;
    text-decoration: none !important;
}

.binder-page .quick-nav .quick-nav-link:hover,
.binder-page .quick-nav .quick-nav-link:focus-visible {
    color: var(--tp-color-text-primary) !important;
    border-color: var(--tp-color-border-strong) !important;
    background: var(--tp-color-surface-muted) !important;
}

.binder-page .quick-nav .quick-nav-link.is-active,
.binder-page .quick-nav .quick-nav-link[aria-current="true"] {
    color: var(--tp-color-link-hover) !important;
    border-color: var(--binder-accent-border) !important;
    background: var(--tp-color-brand-100) !important;
    text-decoration: none !important;
}

.tp-dark .binder-page .quick-nav .quick-nav-link.is-active,
.tp-dark .binder-page .quick-nav .quick-nav-link[aria-current="true"] {
    background: var(--tp-color-brand-200) !important;
    border-color: var(--tp-color-brand-300) !important;
    color: var(--tp-color-brand-900) !important;
}

/* ── Grid + panels ────────────────────────────────────────────────── */

.binder-grid {
    display: grid;
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 14px;
}

.binder-card {
    border: 1px solid var(--tp-color-border);
    border-radius: var(--tp-ui-radius-panel);
    background: var(--tp-color-surface);
    padding: 16px;
    overflow: hidden;
    scroll-margin-top: 128px;
}

.binder-card h2 {
    margin: 0;
    font-size: var(--tp-heading-sm);
    font-weight: 600;
    color: var(--binder-accent-ink);
}

.binder-page .section-head {
    display: flex;
    justify-content: space-between;
    align-items: flex-start;
    gap: 10px;
    margin-bottom: 12px;
}

.binder-page .section-subtitle {
    margin: 4px 0 0;
    color: var(--tp-color-text-muted);
    font-size: 0.86rem;
    line-height: 1.45;
}

.binder-card--properties,
.binder-card--druglikeness,
.binder-card--strings,
.binder-card--provenance,
.binder-card--external,
.binder-card--siblings {
    grid-column: 1 / -1;
}

@media (max-width: 880px) {
    .binder-grid {
        grid-template-columns: minmax(0, 1fr);
    }
}

@media (prefers-reduced-motion: reduce) {
    .binder-hero,
    .binder-page .quick-nav,
    .binder-card {
        animation: none !important;
        transition: none !important;
    }
}

/* ── Structure SVG ────────────────────────────────────────────────── */

.binder-svg-box {
    width: 100%;
    aspect-ratio: 1 / 1;
    max-width: 360px;
    margin: 0 auto;
    background: var(--tp-color-surface-soft);
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 12px;
    overflow: hidden;
    display: grid;
    place-items: center;
}

.binder-svg-box svg {
    width: 100%;
    height: 100%;
    display: block;
}

/* ── Identifiers / dl rows ────────────────────────────────────────── */

.binder-identifiers {
    margin: 0;
    display: flex;
    flex-direction: column;
    gap: 10px;
}

.binder-id-row {
    display: grid;
    grid-template-columns: 160px minmax(0, 1fr);
    gap: 12px;
    align-items: baseline;
}

.binder-id-row dt {
    color: var(--tp-color-text-muted);
    font-size: 0.78rem;
    font-weight: 500;
    letter-spacing: 0.06em;
    text-transform: uppercase;
}

.binder-id-row dd {
    margin: 0;
    color: var(--tp-color-text-primary);
    font-weight: 500;
    overflow-wrap: anywhere;
}

@media (max-width: 640px) {
    .binder-id-row {
        grid-template-columns: 1fr;
        gap: 2px;
    }
}

/* ── Physicochemical properties grid ──────────────────────────────── */

.property-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(180px, 1fr));
    gap: 10px;
}

.property-cell {
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    background: var(--tp-color-surface);
    padding: 10px 12px;
    display: grid;
    gap: 4px;
    min-height: 68px;
    align-content: center;
}

.property-label {
    font-size: var(--tp-font-label);
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.05em;
    color: var(--tp-color-text-muted);
}

.property-label small {
    text-transform: none;
    letter-spacing: 0;
    font-weight: 500;
    color: var(--tp-color-text-muted);
}

.property-value {
    font-size: 1.05rem;
    font-weight: 600;
    color: var(--binder-accent-ink);
    line-height: 1.2;
}

.property-value--text {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.95rem;
    word-break: break-all;
}

.property-unit {
    font-size: 0.78rem;
    font-weight: 500;
    color: var(--tp-color-text-muted);
}

/* ── Drug-likeness ────────────────────────────────────────────────── */

.druglike-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 14px;
}

.druglike-block {
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 12px;
    background: var(--tp-color-surface);
    padding: 14px 16px;
}

.druglike-head {
    display: flex;
    align-items: center;
    justify-content: space-between;
    gap: 10px;
    margin-bottom: 10px;
}

.druglike-title {
    font-size: 1rem;
    font-weight: 600;
    color: var(--binder-accent-ink);
}

.druglike-badge {
    display: inline-flex;
    align-items: center;
    gap: 8px;
    padding: 4px 10px;
    border-radius: 999px;
    font-size: 0.78rem;
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.05em;
    border: 1px solid transparent;
}

.druglike-badge.is-pass {
    background: var(--binder-pass-soft);
    color: var(--binder-pass);
    border-color: var(--binder-pass-border);
}

.druglike-badge.is-fail {
    background: var(--binder-fail-soft);
    color: var(--binder-fail);
    border-color: var(--binder-fail-border);
}

.druglike-badge.is-warn {
    background: var(--binder-warn-soft);
    color: var(--binder-warn);
    border-color: var(--binder-warn-border);
}

.druglike-badge-count {
    font-size: var(--tp-font-label);
    font-weight: 500;
    opacity: 0.8;
    text-transform: none;
    letter-spacing: 0;
}

.druglike-checks {
    margin: 0;
    padding: 0;
    list-style: none;
    display: flex;
    flex-direction: column;
    gap: 6px;
}

.druglike-checks li {
    display: grid;
    grid-template-columns: 22px 1fr auto;
    align-items: center;
    gap: 8px;
    padding: 6px 10px;
    border-radius: 8px;
    background: var(--tp-color-surface-soft);
    border: 1px solid var(--tp-color-border-soft);
    font-size: 0.9rem;
}

.druglike-checks li.is-ok .check-icon {
    color: var(--binder-pass);
    font-weight: 800;
}

.druglike-checks li.is-bad .check-icon {
    color: var(--binder-fail);
    font-weight: 800;
}

.check-name {
    color: var(--tp-color-text-secondary);
}

.check-value {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.85rem;
    font-weight: 600;
    color: var(--binder-accent-ink);
}

.druglike-note {
    margin: 0;
    font-size: 0.9rem;
    line-height: 1.5;
    color: var(--tp-color-text-secondary);
}

.druglike-note code {
    background: var(--tp-color-surface-soft);
}

/* ── Chemical strings (SMILES / InChI / InChIKey) ─────────────────── */

.binder-string-block {
    margin-bottom: 12px;
}

.binder-string-block:last-child {
    margin-bottom: 0;
}

.binder-string-head {
    display: flex;
    justify-content: space-between;
    align-items: center;
    gap: 10px;
    margin-bottom: 6px;
}

.binder-string-label {
    font-size: 0.78rem;
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.06em;
    color: var(--tp-color-text-muted);
}

.binder-string-value {
    margin: 0;
    padding: 10px 12px;
    background: var(--tp-color-surface-soft);
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.85rem;
    line-height: 1.5;
    color: var(--tp-color-text-secondary);
    white-space: pre-wrap;
    overflow-wrap: anywhere;
}

.binder-string-value--short {
    word-break: break-all;
}

/* ── External resources ──────────────────────────────────────────── */

.binder-links {
    margin: 0;
    padding: 0;
    list-style: none;
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(280px, 1fr));
    gap: 8px;
}

.binder-links li {
    display: flex;
    align-items: center;
    gap: 10px;
    padding: 8px 12px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    background: var(--tp-color-surface-soft);
}

.binder-link-category {
    font-size: 0.7rem;
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.06em;
    color: var(--binder-accent-ink);
    background: var(--binder-accent-soft);
    padding: 3px 8px;
    border-radius: 999px;
    border: 1px solid var(--binder-accent-border);
    flex: 0 0 auto;
    white-space: nowrap;
}

.binder-links a {
    color: var(--tp-color-link);
    font-weight: 600;
    text-decoration: none;
    flex: 1;
}

.binder-links a:hover,
.binder-links a:focus-visible {
    color: var(--tp-color-link-hover);
    text-decoration: underline;
    outline: none;
}

/* ── Siblings ────────────────────────────────────────────────────── */

.siblings-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(240px, 1fr));
    gap: 14px;
}

.siblings-group {
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 12px;
    background: var(--tp-color-surface-soft);
    padding: 12px 14px;
}

.siblings-group-title {
    margin: 0 0 4px;
    font-size: 0.85rem;
    font-weight: 500;
    text-transform: uppercase;
    letter-spacing: 0.06em;
    color: var(--binder-accent-ink);
    display: flex;
    align-items: center;
    gap: 8px;
}

.siblings-group-desc {
    margin: 0 0 8px;
    font-size: 0.82rem;
    color: var(--tp-color-text-muted);
    line-height: 1.4;
}

.siblings-col-hint {
    font-weight: 400;
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.75em;
    opacity: 0.8;
}

.siblings-group-count {
    font-size: var(--tp-font-label);
    font-weight: 500;
    color: var(--tp-color-text-muted);
    background: var(--tp-color-surface);
    padding: 1px 8px;
    border-radius: 999px;
    border: 1px solid var(--tp-color-border-soft);
}

.siblings-list {
    margin: 0;
    padding: 0;
    list-style: none;
    display: flex;
    flex-direction: column;
    gap: 4px;
}

.siblings-list li a {
    display: flex;
    align-items: center;
    justify-content: space-between;
    gap: 8px;
    padding: 6px 10px;
    border-radius: 8px;
    text-decoration: none;
    color: var(--tp-color-text-primary);
    transition: background 120ms ease;
}

.siblings-list li a:hover,
.siblings-list li a:focus-visible {
    background: var(--binder-accent-soft);
    outline: none;
}

.siblings-meta {
    font-size: 0.78rem;
    color: var(--tp-color-text-muted);
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
}

.siblings-col-head {
    display: flex;
    justify-content: space-between;
    padding: 0 10px 4px;
    font-size: var(--tp-font-label);
    font-weight: 600;
    letter-spacing: 0.04em;
    text-transform: uppercase;
    color: var(--tp-color-text-muted);
    border-bottom: 1px solid var(--tp-color-border-soft);
    margin-bottom: 4px;
}