/* ============================================================
   Data Sources / Methodology page
   ============================================================ */

.ds-page {
    font-family: "Source Sans 3", "Segoe UI", sans-serif;
    color: var(--tp-ink);
    margin: 0;
    display: grid;
    gap: var(--tp-space-4);
    --ds-accent: var(--tp-color-brand-800);
    --ds-accent-deep: var(--tp-color-brand-900);
    --ds-accent-soft: var(--tp-color-brand-050);
    --ds-accent-border: var(--tp-color-brand-200);
}

.ds-page h1,
.ds-page h2,
.ds-page h3,
.ds-page h4 {
    font-family: "Space Grotesk", "Segoe UI", sans-serif;
    font-weight: 700;
    letter-spacing: 0.2px;
}

/* ── Hero ── */
.ds-eyebrow {
    margin: 6px 0 10px;
    color: var(--tp-color-text-muted);
    font-size: var(--tp-font-label);
    font-weight: 700;
    letter-spacing: 0.08em;
    text-transform: uppercase;
}

.ds-hero-title {
    margin: 0;
    font-size: var(--tp-heading-lg);
    font-weight: 700;
    line-height: 1.1;
    color: var(--ds-accent-deep);
}

.ds-hero-description {
    margin: 10px 0 0;
    color: var(--tp-color-text-secondary);
    font-size: 1rem;
    line-height: 1.42;
    max-width: 920px;
}

/* ── Sticky section nav ── */
.ds-quick-nav {
    position: sticky;
    top: -2px;
    z-index: 25;
    align-self: stretch;
    width: 100%;
    display: flex;
    flex-wrap: nowrap;
    gap: 6px;
    overflow-x: auto;
    padding: 8px 10px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 12px;
    background: linear-gradient(180deg, var(--tp-color-surface) 0%, var(--tp-color-surface-soft) 100%);
    box-shadow: var(--tp-shadow-xs);
    backdrop-filter: blur(3px);
    scrollbar-width: none;
}
.ds-quick-nav::-webkit-scrollbar { display: none; }

.ds-quick-nav-link {
    flex: 0 0 auto;
    display: inline-flex;
    align-items: center;
    white-space: nowrap;
    padding: 0.38rem 0.9rem;
    font-size: 0.82rem;
    font-weight: 600;
    border-radius: 999px;
    border: 1px solid var(--tp-color-border-strong);
    background: linear-gradient(180deg, var(--tp-color-surface) 0%, var(--tp-color-surface-soft) 100%);
    color: var(--tp-color-text-secondary);
    text-decoration: none;
    transition: color 0.15s, border-color 0.15s, background 0.15s;
}
.ds-quick-nav-link:hover {
    color: var(--ds-accent);
    border-color: var(--ds-accent-border);
    background: linear-gradient(180deg, var(--tp-color-surface) 0%, var(--ds-accent-soft) 100%);
    text-decoration: none;
}
.ds-quick-nav-link.is-active {
    color: var(--ds-accent);
    border-color: var(--ds-accent-border);
    border-width: 2px;
    background: linear-gradient(180deg, var(--ds-accent-soft) 0%, var(--tp-color-brand-050) 100%);
    text-decoration: none;
}

/* ── Panel common ── */
.ds-panel { padding: 20px 22px; }

.ds-panel-title {
    margin: 2px 0 0;
    font-size: 1.12rem;
    font-weight: 800;
    color: var(--ds-accent-deep);
    letter-spacing: -0.02em;
}

.ds-panel-subtitle {
    margin: 4px 0 0;
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.76rem;
    color: var(--tp-color-text-muted);
}

.ds-body {
    margin: 16px 0 0;
    color: var(--tp-color-text-secondary);
    font-size: 0.94rem;
    line-height: 1.65;
}

.ds-subsection {
    margin-top: 24px;
    padding-top: 20px;
    border-top: 1px solid var(--tp-color-border-soft);
}

.ds-subsection h3 {
    margin: 0 0 8px;
    font-size: 0.88rem;
    font-weight: 700;
    color: var(--tp-color-text-primary);
    text-transform: uppercase;
    letter-spacing: 0.05em;
}

/* ── Pipeline grid ── */
.ds-pipeline-grid {
    display: grid;
    grid-template-columns: repeat(3, 1fr);
    gap: 10px;
    margin-top: 20px;
}

.ds-pipeline-card {
    padding: 14px 16px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    background: var(--tp-color-surface);
    display: grid;
    gap: 8px;
    align-content: start;
}

.ds-pipeline-card-head {
    display: flex;
    align-items: center;
    gap: 10px;
}

.ds-pipeline-card-head strong {
    font-size: 0.875rem;
    font-weight: 700;
    color: var(--tp-color-text-primary);
}

.ds-pipeline-card p {
    margin: 0;
    font-size: 0.85rem;
    color: var(--tp-color-text-secondary);
    line-height: 1.58;
}

.ds-stage-tag {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.73rem;
    font-weight: 700;
    color: var(--ds-accent);
    background: var(--ds-accent-soft);
    border: 1px solid var(--ds-accent-border);
    border-radius: 5px;
    padding: 2px 7px;
    white-space: nowrap;
    flex-shrink: 0;
}

/* ── Field list (protein data) ── */
.ds-field-list {
    margin-top: 16px;
    display: grid;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    overflow: hidden;
}

.ds-field-row {
    display: grid;
    grid-template-columns: 140px 1fr;
    gap: 16px;
    padding: 10px 14px;
    border-bottom: 1px solid var(--tp-color-border-soft);
    align-items: baseline;
}

.ds-field-row:last-child { border-bottom: none; }
.ds-field-row:nth-child(even) { background: var(--tp-color-surface-soft); }

.ds-field-name {
    font-size: 0.82rem;
    font-weight: 700;
    color: var(--tp-color-text-primary);
}

.ds-field-desc {
    font-size: 0.85rem;
    color: var(--tp-color-text-secondary);
    line-height: 1.5;
}

/* ── Callout ── */
.ds-callout {
    margin-top: 16px;
    padding: 13px 15px;
    border-radius: 9px;
    border: 1px solid var(--tp-color-border-soft);
    background: var(--tp-color-surface-muted);
    font-size: 0.875rem;
    color: var(--tp-color-text-secondary);
    line-height: 1.62;
}

/* ── Priority stack ── */
.ds-priority-stack {
    margin-top: 16px;
    display: grid;
    gap: 1px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 12px;
    overflow: hidden;
}

.ds-priority-row {
    display: flex;
    gap: 16px;
    align-items: flex-start;
    padding: 16px 18px;
    background: var(--tp-color-surface);
    border-bottom: 1px solid var(--tp-color-border-soft);
}

.ds-priority-row:last-child { border-bottom: none; }
.ds-priority-row:nth-child(even) { background: var(--tp-color-surface-soft); }

.ds-priority-badge {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    width: 26px;
    height: 26px;
    border-radius: 50%;
    font-size: 0.8rem;
    font-weight: 800;
    flex-shrink: 0;
    margin-top: 1px;
}

.ds-priority-badge--1 {
    background: var(--tp-color-success-bg);
    color: var(--tp-color-success-ink);
    border: 1.5px solid var(--tp-color-success-border);
}

.ds-priority-badge--2 {
    background: var(--tp-color-warning-bg);
    color: var(--tp-color-warning-ink);
    border: 1.5px solid var(--tp-color-warning-border);
}

.ds-priority-badge--3 {
    background: var(--tp-color-surface-muted);
    color: var(--tp-color-text-muted);
    border: 1.5px solid var(--tp-color-border);
}

.ds-priority-body {
    display: grid;
    gap: 3px;
}

.ds-priority-body strong {
    font-size: 0.9rem;
    font-weight: 700;
    color: var(--tp-color-text-primary);
}

.ds-priority-source {
    font-size: 0.76rem;
    color: var(--tp-color-text-muted);
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
}

.ds-priority-body p {
    margin: 4px 0 0;
    font-size: 0.875rem;
    color: var(--tp-color-text-secondary);
    line-height: 1.58;
}

/* ── Score table ── */
.ds-score-table {
    display: grid;
    gap: 4px;
    margin-top: 12px;
}

.ds-score-row {
    display: flex;
    align-items: center;
    gap: 12px;
    padding: 6px 10px;
    border-radius: 7px;
    font-size: 0.84rem;
}

.ds-score-row--high   { background: var(--tp-color-success-bg); color: var(--tp-color-success-ink); }
.ds-score-row--medium { background: var(--tp-color-warning-bg); color: var(--tp-color-warning-ink); }
.ds-score-row--low    { background: var(--tp-color-danger-bg);  color: var(--tp-color-danger-ink); }
.ds-score-row--none   { background: var(--tp-color-surface-muted); color: var(--tp-color-text-secondary); }

.ds-score-range {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.78rem;
    font-weight: 700;
    min-width: 64px;
    flex-shrink: 0;
}

/* ── Tool columns (binding sites) ── */
.ds-tool-cols {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 14px;
    margin-top: 16px;
}

.ds-tool-block {
    padding: 16px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    background: var(--tp-color-surface);
    display: grid;
    gap: 10px;
    align-content: start;
}

.ds-tool-head {
    display: flex;
    align-items: baseline;
    gap: 8px;
}

.ds-tool-name {
    font-size: 1.05rem;
    font-weight: 800;
    color: var(--ds-accent-deep);
    letter-spacing: -0.01em;
}

.ds-tool-ver {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.73rem;
    color: var(--tp-color-text-muted);
}

/* ── DB grid (InterProScan) ── */
.ds-db-grid {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 1px;
    margin-top: 12px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    overflow: hidden;
}

.ds-db-row {
    display: flex;
    gap: 10px;
    align-items: baseline;
    padding: 9px 12px;
    background: var(--tp-color-surface);
    border-bottom: 1px solid var(--tp-color-border-soft);
}

.ds-db-row:nth-child(odd):last-child,
.ds-db-row:last-child,
.ds-db-row:nth-last-child(2):nth-child(odd) { border-bottom: none; }

.ds-db-name {
    font-size: 0.8rem;
    font-weight: 700;
    color: var(--tp-color-text-primary);
    white-space: nowrap;
    flex-shrink: 0;
    min-width: 110px;
}

.ds-db-desc {
    font-size: 0.80rem;
    color: var(--tp-color-text-muted);
    line-height: 1.4;
}

/* ── Target profile grid ── */
.ds-profile-grid {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 10px;
    margin-top: 16px;
}

.ds-profile-card {
    padding: 15px 16px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    background: var(--tp-color-surface);
    display: grid;
    gap: 8px;
    align-content: start;
}

.ds-profile-card-head {
    display: grid;
    gap: 2px;
}

.ds-profile-label {
    font-size: 0.88rem;
    font-weight: 700;
    color: var(--tp-color-text-primary);
}

.ds-profile-tool {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.72rem;
    color: var(--tp-color-text-muted);
}

.ds-profile-card > p {
    margin: 0;
    font-size: 0.85rem;
    color: var(--tp-color-text-secondary);
    line-height: 1.58;
}

.ds-desirable {
    font-size: 0.82rem !important;
    color: var(--tp-color-text-muted) !important;
    padding-top: 6px;
    border-top: 1px solid var(--tp-color-border-soft);
}

/* ── Ligands table ── */
.ds-table {
    width: 100%;
    border-collapse: collapse;
    font-size: 0.875rem;
    margin-top: 16px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    overflow: hidden;
}

.ds-table th {
    background: var(--tp-color-surface-muted);
    color: var(--tp-color-text-muted);
    font-size: 0.73rem;
    font-weight: 700;
    text-transform: uppercase;
    letter-spacing: 0.07em;
    padding: 9px 12px;
    text-align: left;
    border-bottom: 1px solid var(--tp-color-border-soft);
}

.ds-table td {
    padding: 9px 12px;
    color: var(--tp-color-text-secondary);
    border-bottom: 1px solid var(--tp-color-border-soft);
    line-height: 1.45;
    vertical-align: top;
}

.ds-table tr:last-child td { border-bottom: none; }
.ds-table tr:nth-child(even) td { background: var(--tp-color-surface-soft); }

/* ── Definitions (pChEMBL, Tanimoto) ── */
.ds-def-list {
    margin-top: 14px;
    display: grid;
    gap: 1px;
    border: 1px solid var(--tp-color-border-soft);
    border-radius: 10px;
    overflow: hidden;
}

.ds-def-row {
    display: grid;
    grid-template-columns: 100px 1fr;
    gap: 16px;
    padding: 10px 14px;
    background: var(--tp-color-surface);
    border-bottom: 1px solid var(--tp-color-border-soft);
    align-items: baseline;
}

.ds-def-row:last-child { border-bottom: none; }
.ds-def-row:nth-child(even) { background: var(--tp-color-surface-soft); }

.ds-def-term {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.82rem;
    font-weight: 700;
    color: var(--ds-accent);
}

.ds-def-body {
    font-size: 0.85rem;
    color: var(--tp-color-text-secondary);
    line-height: 1.55;
}

/* ── Drug-likeness list ── */
.ds-dl-list {
    margin-top: 8px;
}

.ds-dl-row {
    padding: 16px 0;
    border-bottom: 1px solid var(--tp-color-border-soft);
    display: grid;
    gap: 8px;
}

.ds-dl-row:last-child { border-bottom: none; }

.ds-dl-head {
    display: flex;
    align-items: center;
    gap: 10px;
}

.ds-dl-tag {
    font-family: "JetBrains Mono", "SFMono-Regular", Menlo, Consolas, monospace;
    font-size: 0.76rem;
    font-weight: 800;
    color: var(--ds-accent);
    background: var(--ds-accent-soft);
    border: 1px solid var(--ds-accent-border);
    border-radius: 5px;
    padding: 2px 8px;
    flex-shrink: 0;
}

.ds-dl-name {
    font-size: 0.9rem;
    font-weight: 700;
    color: var(--tp-color-text-primary);
}

.ds-dl-row > p {
    margin: 0;
    font-size: 0.875rem;
    color: var(--tp-color-text-secondary);
    line-height: 1.62;
}

/* ── Caveats ── */
.ds-caveats {
    padding: 0;
    margin: 16px 0 0;
    list-style: none;
    display: grid;
}

.ds-caveats li {
    padding: 14px 0;
    border-bottom: 1px solid var(--tp-color-border-soft);
    color: var(--tp-color-text-secondary);
    font-size: 0.93rem;
    line-height: 1.65;
}

.ds-caveats li:last-child { border-bottom: none; }
.ds-caveats strong { color: var(--tp-color-text-primary); }

/* ── Responsive ── */
@media (max-width: 880px) {
    .ds-pipeline-grid { grid-template-columns: 1fr 1fr; }
    .ds-tool-cols,
    .ds-profile-grid,
    .ds-db-grid { grid-template-columns: 1fr; }
}

@media (max-width: 600px) {
    .ds-pipeline-grid { grid-template-columns: 1fr; }
    .ds-field-row { grid-template-columns: 1fr; gap: 3px; }
    .ds-def-row { grid-template-columns: 1fr; gap: 4px; }
    .ds-hero-title { font-size: 1.8rem; }
}

/* ── Dark mode ── */
.tp-dark .ds-pipeline-card,
.tp-dark .ds-tool-block,
.tp-dark .ds-profile-card,
.tp-dark .ds-priority-row,
.tp-dark .ds-db-row {
    background: var(--tp-color-surface-soft);
}

.tp-dark .ds-priority-row:nth-child(even),
.tp-dark .ds-db-row:nth-child(odd),
.tp-dark .ds-field-row:nth-child(even),
.tp-dark .ds-table tr:nth-child(even) td,
.tp-dark .ds-def-row:nth-child(even) {
    background: var(--tp-color-surface-muted);
}