Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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6 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters EC Number: 2.1.1.-

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EC Number: 2.1.1.- ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_02954 Ribosomal protein L11 methyltransferase prmA AlphaFold + ColabFold
2.1.1.-
GO:0008276Catalysis of the transfer of a methyl group (CH3-) to a protein. GO:0006479The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +36 total
0.985 No Hit 0.0% —
2 KP13_04188 Protein smtA smtA AlphaFold + ColabFold
2.1.1.-
GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0097697Catalysis of the reaction: 5-carboxymethoxyuridine34 in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine34 in tRNA + S-adenosyl-L-homocysteine. The methylation occurs on the modified base. GO:0032259The process in which a methyl group is covalently attached to a molecule. +14 total
0.933 No Hit 0.0% —
3 KP13_04048 Phage DNA adenine methylase AlphaFold + ColabFold
2.1.1.-
GO:0008168Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0006306OBSOLETE. The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. GO:0003676Binding to a nucleic acid. +36 total
0.868 No Hit 0.0% —
4 KP13_02653 putative cytosine-N4-specific DNA methylase AlphaFold + ColabFold
2.1.1.-
GO:0090124OBSOLETE. The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule. GO:0006306OBSOLETE. The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. GO:0008170Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. +47 total
0.653 No Hit 0.0% —
5 KP13_05628 Site-specific DNA-methyltransferase (cytosine-N4-specific) AlphaFold + ColabFold
2.1.1.-
GO:0090124OBSOLETE. The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule. GO:0006306OBSOLETE. The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. GO:0008170Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. +47 total
0.434 No Hit 0.0% —
6 KP13_01848 Type 4 prepilin-like proteins leader peptide-processing enzyme bifunctional protein pulO AlphaFold + ColabFold
2.1.1.- 3.4.23.43
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0004190Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +36 total
0.133 No Hit 0.0% —
Page 1 of 1 · 6 total proteins