Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

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2 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters EC Number: 2.7.1.121

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EC Number: 2.7.1.121 ×
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
1 KP13_02848 PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit dhaK dhaK AlphaFold + ColabFold
2.7.1.121
GO:0004371Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H+. GO:0006071The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. GO:0005829The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. +25 total
0.727 Hit 48.1% 2.19e-36
2 KP13_02850 PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM dhaM AlphaFold + ColabFold
2.7.1.121
GO:0047324Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate. GO:0016310The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. GO:0016772Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). +36 total
0.049 No Hit 0.0% —
Page 1 of 1 · 2 total proteins