Proteins

Genome: KpKP13

Description: Klebsiella pneumoniae subsp. pneumoniae Kp13, complete sequence

Search, filter, and prioritize proteins.

Export view
5842 proteins

Scoring formula None

Sorted by Druggability (descending)

Applied filters No active filters

Search query No active search

Rows per page 25

Rows
# Protein Description Gene Structure EC GO Druggability FPocket druggability score for the preferred structure (0–1): experimental structure when available, otherwise predicted model. ≥ 0.7 highly druggable · ≥ 0.4 moderately druggable · < 0.4 low druggability. Human off-target BLASTP against the human proteome. Hit means at least one human match was detected at e-value <= 1e-5. Prefer No hit for pathogen-selective targets. Human identity (%) Best human BLAST identity percentage. Human E-value Best human BLAST E-value.
2176 KP13_31536 putative transposase AlphaFold + ColabFold – – 0.664 No Hit 0.0% —
2177 KP13_03224 Mannonate dehydratase uxuA AlphaFold + ColabFold
4.2.1.8
GO:0008927Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. GO:0006064The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid. GO:0008198Binding to a ferrous iron ion, Fe(II). +25 total
0.664 No Hit 0.0% —
2178 KP13_01810 Elongation factor Ts tsf AlphaFold + ColabFold –
GO:0003746Functions in chain elongation during polypeptide synthesis at the ribosome. GO:0005515Binding to a protein. GO:0006414The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. +14 total
0.664 Hit 36.1% 3.51e-12
2179 KP13_05517 Nitronate monooxygenase AlphaFold + ColabFold –
GO:0018580Catalysis of the reaction: ethylnitronate + O2 = acetaldehyde + nitrite.
0.663 No Hit 0.0% —
2180 KP13_05363 HTH-type transcriptional regulator ttuA AlphaFold + ColabFold –
GO:0006355Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0003700A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0032993A macromolecular complex containing both protein and DNA molecules. +14 total
0.663 No Hit 0.0% —
2181 KP13_05355 Anthranilate synthase component 1 trpE AlphaFold + ColabFold
4.1.3.27
GO:0004049Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate. GO:0009058A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. GO:0046872Binding to a metal ion. +14 total
0.663 No Hit 0.0% —
2182 KP13_05259 putative transport protein AlphaFold + ColabFold
2.7.7.65
GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0052621Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H+. GO:0005525Binding to GTP, guanosine triphosphate. +25 total
0.663 No Hit 0.0% —
2183 KP13_05106 putative dioxygenase AlphaFold + ColabFold –
GO:0051213Catalysis of the incorporation of both atoms of molecular oxygen (O2) into the substrate. GO:0046872Binding to a metal ion.
0.663 No Hit 0.0% —
2184 KP13_04985 RND efflux system, membrane fusion protein AlphaFold + ColabFold –
GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
0.663 No Hit 0.0% —
2185 KP13_04955 Glyoxylate/hydroxypyruvate reductase A bifunctional protein ghrA AlphaFold + ColabFold
1.1.1.79 1.1.1.81
GO:0016618Catalysis of the reaction: (R)-glycerate + NAD(P)+ = 3-hydroxypyruvate + NAD(P)H + H+. GO:0051287Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. GO:0030267Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+. +36 total
0.663 Hit 37.5% 2.30e-06
2186 KP13_04815 hypothetical protein ColabFold – – 0.663 No Hit 0.0% —
2187 KP13_32079 hypothetical protein AlphaFold + ColabFold – – 0.662 No Hit 0.0% —
2188 KP13_05547 Phosphotriesterase family protein AlphaFold + ColabFold –
GO:0016788Catalysis of the hydrolysis of any ester bond. GO:0008270Binding to a zinc ion (Zn). GO:0009056A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
0.662 Hit 35.5% 3.60e-35
2189 KP13_05079 hypothetical protein ColabFold – – 0.662 No Hit 0.0% —
2190 KP13_04481 Pyrimidine-specific ribonucleoside hydrolase rihA rihA AlphaFold + ColabFold
3.2.-.-
GO:0006206The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. GO:0045437Catalysis of the reaction: H2O + uridine = ribofuranose + uracil. GO:0016799Catalysis of the hydrolysis of any N-glycosyl bond. +47 total
0.662 No Hit 0.0% —
2191 KP13_03787 hypothetical protein AlphaFold + ColabFold – – 0.662 No Hit 0.0% —
2192 KP13_02299 putative propanediol utilization protein AlphaFold + ColabFold
2.7.1.177
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0005737The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0016301Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. +14 total
0.662 No Hit 0.0% —
2193 KP13_01526 High-affinity branched-chain amino acid transport ATP-binding protein braF braF AlphaFold + ColabFold –
GO:0005524Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0016887Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. +710 total
0.662 Hit 34.4% 4.79e-06
2194 KP13_01465 Outer-membrane lipoprotein lolB lolB AlphaFold + ColabFold –
GO:0009279A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0015031The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0044874A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.
0.662 No Hit 0.0% —
2195 KP13_00901 Bacteriophage head-to-tail connecting protein AlphaFold + ColabFold – – 0.662 No Hit 0.0% —
2196 KP13_03106 hypothetical protein AlphaFold + ColabFold – – 0.661 No Hit 0.0% —
2197 KP13_01179 Auxin efflux carrier mdcF AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0005886The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
0.661 Hit 24.0% 1.26e-07
2198 KP13_32386 hypothetical protein ColabFold – – 0.66 No Hit 0.0% —
2199 KP13_15122 Arabinose-proton symporter araE AlphaFold + ColabFold –
GO:0016020A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. GO:0022857Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0055085The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. +36 total
0.66 Hit 37.4% 2.05e-45
2200 KP13_04100 Inner membrane protein AlphaFold + ColabFold –
GO:0004792Catalysis of the reaction: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H+.
0.66 No Hit 0.0% —
Page of 234 · 5842 total proteins