Human curated protein

O00116

Alkyldihydroxyacetonephosphate synthase, peroxisomal

Gene: AGPS Organism: Homo sapiens Reviewed UniProt

All human targets

Length 658 aa

Mass 72,912 Da

Annotation score 5/5

Entry version 205

Ligand records 166

Overview

Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e.

Subunit structure

Homodimer

Publications

Nucleotide sequence of human alkyl-dihydroxyacetonephosphate synthase cDNA reveals the presence of a peroxisomal targeting signal 2.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Ether lipid synthesis: purification and identification of alkyl dihydroxyacetone phosphate synthase from guinea-pig liver.
A quantitative atlas of mitotic phosphorylation.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Initial characterization of the human central proteome.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.

Identifiers

Gene: AGPS
UniProt: O00116
Organism: Homo sapiens (taxon 9606)

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Subcellular location

Peroxisome membrane Peroxisome

Keywords

Acetylation Cataract Disease variant Dwarfism FAD Flavoprotein Lipid biosynthesis Lipid metabolism Membrane Peroxisome Phosphoprotein Proteomics identification Reference proteome Rhizomelic chondrodysplasia punctata Transferase Transit peptide

Function

Molecular function, catalytic activity, and Gene Ontology annotations.

1 EC 6 GO

Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis

EC 2.5.1.26 RHEA:36171

a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)

RHEA:40659

hexadecan-1-ol + 1-hexadecanoylglycerone 3-phosphate = 1-O-hexadecylglycerone 3-phosphate + hexadecanoate + H(+)

RHEA:40727

1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate

Biological process

ether lipid biosynthetic process lipid biosynthetic process

Cellular component

cytosol membrane mitochondrion peroxisomal matrix peroxisomal membrane peroxisome

Molecular function

alkylglycerone-phosphate synthase activity FAD binding

Sequence

658 amino acids

MAEAAAAAGGTGLGAGASYGSAADRDRDPDPDRAGRRLRVLSGHLLGRPREALSTNECKARRAASAATAAPTATPAAQESGTIPKKRQEVMKWNGWGYNDSKFIFNKKGQIELTGKRYPLSGMGLPTFKEWIQNTLGVNVEHKTTSKASLNPSDTPPSVVNEDFLHDLKETNISYSQEADDRVFRAHGHCLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWVSTRASGMKKNIYGNIEDLVVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPVPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNKQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYIRDLALEYYVLGESFETSAPWDRVVDLCRNVKERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKEYVDPNNIFGNRNLL

Chain

59–658 Alkyldihydroxyacetonephosphate synthase, peroxisomal

Domain

202–384 FAD-binding PCMH-type

Region

1–41 Disordered

63–86 Disordered

615–617 Important for enzyme activity

654–658 Important for enzyme activity

Ligand evidence

Ligands grouped by evidence source, via the same LigQ_2 pipeline used across Target.

166 records

Chemistry signal

Structural and bioactivity evidence are both available for this target.

Direct evidence 0 same-protein records

Transferred evidence 116 records from similar proteins

Structural ligands 63 0 loaded crystals

Measured bioactivity 53 direct and transferred ChEMBL records

Proposed compounds 50 similarity-based ZINC candidates

No co-crystallized ligand found for this exact protein.

Ligand	Source crystal	UniProt (homolog)	MW · LogP · TPSA	Lipinski	PAINS	SMILES
0SK RCSB PDB	4F4Q	A0R607	417.4 Da LogP 3.21 TPSA 83.9	✓ Ro5	✓ Clean	`C[C@H]1COC2(O1)CCN(CC2)C3=NC(=O)c4cc(cc(c4S3)NO…`
0SK RCSB PDB	6HEZ	P9WJF1	417.4 Da LogP 3.21 TPSA 83.9	✓ Ro5	✓ Clean	`C[C@H]1COC2(O1)CCN(CC2)C3=NC(=O)c4cc(cc(c4S3)NO…`
0T4 RCSB PDB	4FDN	P9WJF1	324.3 Da LogP 4.00 TPSA 61.4	✓ Ro5	✓ Clean	`CC(c1ccccc1)NC(=O)c2cc(cc(c2)NO)C(F)(F)F`
0T5 RCSB PDB	4FDO	P9WJF1	338.3 Da LogP 4.10 TPSA 72.2	✓ Ro5	✓ Clean	`CC(c1ccccc1)NC(=O)c2cc(cc(c2)[N+](=O)[O-])C(F)(…`
1DO RCSB PDB	4BC7	P97275	186.3 Da LogP 3.90 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCCCCCCO`
1W6 RCSB PDB	4KW5	P9WJF1	375.4 Da LogP 3.50 TPSA 97.4	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1ccsc1NC(=O)c2nc3ccccc3s2`
245 RCSB PDB	4O95	E3T1W8	247.7 Da LogP 3.38 TPSA 54.0	✓ Ro5	✓ Clean	`c1ccc(cc1)NC(=O)Nc2ccnc(c2)Cl`
26J RCSB PDB	4NCR	P9WJF1	442.5 Da LogP 4.18 TPSA 68.7	✓ Ro5	✓ Clean	`c1c(cc(c2c1C(=O)N=C(S2)N3CCN(CC3)CC4CCCCC4)NO)C…`
2HG RCSB PDB	6LPP	Q8N465	148.1 Da LogP -0.70 TPSA 94.8	✓ Ro5	✓ Clean	`C(CC(=O)O)[C@H](C(=O)O)O`
2J3 RCSB PDB	4P8T	P9WJF1	192.3 Da LogP 0.17 TPSA 58.9	✓ Ro5	✓ Clean	`C[C@H](CO)OC[C@@H](C)OC[C@@H](C)O`
2R2 RCSB PDB	4PFD	P9WJF1	432.4 Da LogP 2.94 TPSA 88.8	✓ Ro5	✓ Clean	`Cc1c(cc2c(c1[N+](=O)[O-])sc(n2)C(=O)N3CCN(CC3)C…`
36C RCSB PDB	4P8L	P9WJF1	365.3 Da LogP 4.10 TPSA 75.1	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)F`
38C RCSB PDB	4P8Y	P9WJF1	377.3 Da LogP 3.97 TPSA 84.3	✓ Ro5	✓ Clean	`COc1ccc(cc1)CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O`
67K RCSB PDB	5I1W	H8Y6P5	200.2 Da LogP 1.66 TPSA 63.1	✓ Ro5	✓ Clean	`c1ccnc(c1)c2cc(cc(n2)C=O)O`
67L RCSB PDB	5I1W	H8Y6P5	202.2 Da LogP 1.34 TPSA 66.2	✓ Ro5	✓ Clean	`c1ccnc(c1)c2cc(cc(n2)CO)O`
973 RCSB PDB	2Q85	P08373	348.8 Da LogP 5.36 TPSA 46.5	1 viol.	✓ Clean	`c1ccc2c(c1)cccc2\C=C/3\C(=C(C(=O)O3)c4ccc(cc4)C…`
9T2 RCSB PDB	5OEP	P9WJF1	393.4 Da LogP 3.64 TPSA 97.4	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1cc(sc1NC(=O)c2nc3ccccc3s2)F`
AKG RCSB PDB	6LPX	Q8N465	146.1 Da LogP -0.50 TPSA 91.7	✓ Ro5	✓ Clean	`C(CC(=O)O)C(=O)C(=O)O`
AKY RCSB PDB	2IPI	Q0PCD7	811.9 Da LogP 3.16 TPSA 217.0	2 viol.	Alert	`CC[C@]1(C[C@@H](c2c(cc3c(c2O)C(=O)c4c(cccc4O)C3…`
AWB RCSB PDB	5AE3	P97275	548.6 Da LogP 3.48 TPSA 157.3	1 viol.	✓ Clean	`CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1…`
B2Z RCSB PDB	5AE1	P97275	341.4 Da LogP 3.37 TPSA 77.8	✓ Ro5	✓ Clean	`C[C@@H](CC(=O)N[C@H](C)c1ccc2c(c1)NC(=O)N2)c3cc…`
BEZ RCSB PDB	5FXF	Q0SBK1	122.1 Da LogP 1.38 TPSA 37.3	✓ Ro5	✓ Clean	`c1ccc(cc1)C(=O)O`
CIY RCSB PDB	5FXE	Q0SBK1	178.2 Da LogP 1.61 TPSA 46.5	✓ Ro5	✓ Clean	`COc1cc(ccc1O)/C=C/C=O`
EDZ RCSB PDB	5HQX	E3T1W8	264.3 Da LogP 1.72 TPSA 87.1	✓ Ro5	✓ Clean	`c1ccc(c(c1)CCO)NC(=O)Nc2cnns2`
EEB RCSB PDB	1MBB	P08373	693.4 Da LogP -3.76 TPSA 332.2	3 viol.	✓ Clean	`CCC(C(=O)O)O[C@@H]1[C@H]([C@H](O[C@@H]([C@H]1O)…`
EPT RCSB PDB	1AHZ	P56216	192.3 Da LogP 3.91 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCc1ccc(cc1)O`
EPU RCSB PDB	1UXY	P08373	677.4 Da LogP -4.03 TPSA 332.2	3 viol.	✓ Clean	`CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O[P@@]…`
EQ8 RCSB PDB	6G83	P9WJF1	491.5 Da LogP 1.94 TPSA 101.6	✓ Ro5	✓ Clean	`c1c(cc(c2c1C(=O)N=C(S2)N3CCN(CC3)S(=O)(=O)C4CCC…`
EUG RCSB PDB	1DZN	P56216	164.2 Da LogP 2.43 TPSA 29.5	✓ Ro5	✓ Clean	`C/C=C/c1ccc(c(c1)OC)O`
F6T RCSB PDB	6GOU	P97275	345.3 Da LogP 2.94 TPSA 77.8	✓ Ro5	✓ Clean	`C[C@@H](CC(=O)NCc1ccc2c(c1)NC(=O)N2)c3c(cccc3F)F`
FAA RCSB PDB	1AHU	P56216	891.7 Da LogP -2.41 TPSA 377.0	3 viol.	✓ Clean	`Cc1cc2c(cc1C)[N+](=C3C(=O)NC(=O)N=C3N2C[C@@H]([…`
FCR RCSB PDB	1E0Y	P56216	162.1 Da LogP 2.41 TPSA 20.2	✓ Ro5	✓ Clean	`c1cc(ccc1C(F)(F)F)O`
FDZ RCSB PDB	5HMR	E3T1W8	304.3 Da LogP 3.08 TPSA 76.1	✓ Ro5	✓ Clean	`c1cc(cc(c1)OC(F)(F)F)NC(=O)Nc2cnns2`
FYC RCSB PDB	5AE2	P97275	325.3 Da LogP 2.71 TPSA 77.8	✓ Ro5	✓ Clean	`C/C(=C\c1ccccc1F)/C(=O)NCc2ccc3c(c2)NC(=O)N3`
G1H RCSB PDB	6HF0	P9WJF1	371.3 Da LogP 3.88 TPSA 89.5	✓ Ro5	✓ Clean	`C[C@@H]1CCC[C@@H](N1C2=NC(=O)c3cc(cc(c3O2)[N+](…`
G1T RCSB PDB	6HFV	P9WJF1	345.3 Da LogP 3.47 TPSA 65.5	✓ Ro5	✓ Clean	`c1c(cc(c2c1C(=O)N=C(S2)N3CCCCC3)NO)C(F)(F)F`
KQS RCSB PDB	5ADZ	P97275	327.4 Da LogP 2.81 TPSA 77.8	✓ Ro5	✓ Clean	`C[C@@H](CC(=O)NCc1ccc2c(c1)NC(=O)N2)c3ccccc3F`
LAC RCSB PDB	6LPT	Q8N465	90.1 Da LogP -0.55 TPSA 57.5	✓ Ro5	✓ Clean	`C[C@H](C(=O)O)O`
LUZ RCSB PDB	6V43	A9D9D1	164.1 Da LogP -0.99 TPSA 91.5	✓ Ro5	✓ Clean	`c1cnc2c(n1)C(=O)NC(=O)N2`
MLI RCSB PDB	4PVJ	B2ZWE9	102.0 Da LogP -3.12 TPSA 80.3	✓ Ro5	✓ Clean	`C(C(=O)[O-])C(=O)[O-]`
MLT RCSB PDB	6LPQ	Q8N465	134.1 Da LogP -1.09 TPSA 94.8	✓ Ro5	✓ Clean	`C([C@H](C(=O)O)O)C(=O)O`
N77 RCSB PDB	4PFA	P9WJF1	384.3 Da LogP 2.68 TPSA 101.2	✓ Ro5	✓ Clean	`c1cc(cnc1)CNC(=O)c2[n+](c3cc(cc(c3s2)NO)C(F)(F)…`
NCR RCSB PDB	1AHV	P56216	153.1 Da LogP 1.61 TPSA 63.4	✓ Ro5	✓ Clean	`Cc1ccc(c(c1)[N+](=O)[O-])O`
O95 RCSB PDB	4P8H	P9WJF1	414.4 Da LogP 3.19 TPSA 87.0	✓ Ro5	✓ Clean	`Cc1c(cc2c(c1NO)sc(n2)C3=N[C@@H](CO3)C(=O)N4CCCC…`
OHZ RCSB PDB	6YAP	E3T1W8	374.7 Da LogP 4.42 TPSA 70.6	✓ Ro5	✓ Clean	`c1ccc(c(c1)CCO)NC(=O)Nc2cc(cc(c2)Cl)OC(F)(F)F`
OHZ RCSB PDB	6YAQ	A0A1D6QQD6	374.7 Da LogP 4.42 TPSA 70.6	✓ Ro5	✓ Clean	`c1ccc(c(c1)CCO)NC(=O)Nc2cc(cc(c2)Cl)OC(F)(F)F`
OJ2 RCSB PDB	6YAO	E3T1W8	340.3 Da LogP 3.76 TPSA 70.6	✓ Ro5	✓ Clean	`c1ccc(c(c1)CCO)NC(=O)Nc2cccc(c2)OC(F)(F)F`
P95 RCSB PDB	5OEQ	P9WJF1	382.4 Da LogP 3.05 TPSA 109.8	✓ Ro5	✓ Clean	`c1cnc(nc1)NC(=O)c2ccsc2NC(=O)c3nc4cnccc4s3`
PCR RCSB PDB	1DIQ	P09788	108.1 Da LogP 1.70 TPSA 20.2	✓ Ro5	✓ Clean	`Cc1ccc(cc1)O`
PE5 RCSB PDB	4UD8	O64743	398.5 Da LogP 0.13 TPSA 94.1	✓ Ro5	✓ Clean	`CCOCCOCCOCCOCCOCCOCCOCCOCCO`
PL3 RCSB PDB	2UUU	O96759	242.4 Da LogP 5.46 TPSA 20.2	1 viol.	✓ Clean	`CCCCCCCCCCCCCCCCO`
R26 RCSB PDB	4P8T	P9WJF1	372.3 Da LogP 3.83 TPSA 98.9	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)C#N`
R57 RCSB PDB	4P8N	P9WJF1	395.3 Da LogP 4.11 TPSA 84.3	✓ Ro5	✓ Clean	`COc1ccc(cc1F)CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O`
R58 RCSB PDB	4P8M	P9WJF1	391.3 Da LogP 4.36 TPSA 84.3	✓ Ro5	✓ Clean	`CCOc1ccc(cc1)CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O`
RG2 RCSB PDB	4P8P	P9WJF1	381.7 Da LogP 4.61 TPSA 75.1	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)Cl`
S2G RCSB PDB	6LPU	Q8N465	148.1 Da LogP -0.70 TPSA 94.8	✓ Ro5	✓ Clean	`C(CC(=O)O)[C@@H](C(=O)O)O`
SLX RCSB PDB	3FW9	P30986	327.4 Da LogP 2.77 TPSA 62.2	✓ Ro5	Alert	`COc1ccc2c(c1O)C[N@]3CCc4cc(c(cc4[C@@H]3C2)O)OC`
TIR RCSB PDB	2Y3R	D3Y1I2	403.5 Da LogP 2.09 TPSA 105.1	✓ Ro5	✓ Clean	`C[C@H]1[C@H]2[C@H](C=C([C@](O2)(O[C@@H]1[C@H](C…`
TRK RCSB PDB	2Y3R	D3Y1I2	401.5 Da LogP 2.30 TPSA 101.9	✓ Ro5	✓ Clean	`C[C@H]1[C@H]2C(=O)C=C([C@](O2)(O[C@@H]1[C@H](C)…`
V55 RCSB PDB	5FXP	Q0SBK1	152.1 Da LogP 1.21 TPSA 46.5	✓ Ro5	✓ Clean	`COc1cc(ccc1O)C=O`
XE RCSB PDB	4PWB	B2ZWE9	131.3 Da LogP 0.00 TPSA 0.0	✓ Ro5	✓ Clean	`[Xe]`
Y22 RCSB PDB	4P8C	P9WJF1	415.3 Da LogP 4.98 TPSA 75.1	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)C(F…`
ZME RCSB PDB	5HHZ	E3T1W8	199.2 Da LogP 1.45 TPSA 59.4	✓ Ro5	✓ Clean	`Cc1ccn(c1)c2c3c([nH]cn3)ncn2`

No matches.

Ligand	UniProt (homolog)	pchembl	MW · LogP · TPSA	Lipinski	PAINS	SMILES
CHEMBL4164183 ChEMBL	Q15392	10.00 ~0.1 nM	332.5 Da LogP 4.55 TPSA 40.5	✓ Ro5	✓ Clean	`C[C@H](CO)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](O)CC…`
CHEMBL352837 ChEMBL	Q15392	9.15 ~0.7 nM	401.6 Da LogP 5.43 TPSA 40.5	1 viol.	✓ Clean	`C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C…`
CHEMBL4174848 ChEMBL	Q15392	8.60 ~2.5 nM	332.5 Da LogP 4.55 TPSA 40.5	✓ Ro5	✓ Clean	`C[C@H](CO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)C…`
CHEMBL4170755 ChEMBL	Q15392	8.54 ~2.9 nM	547.6 Da LogP 3.10 TPSA 24.1	1 viol.	✓ Clean	`C[C@H](/C=C/c1cc[n+](C)cc1)[C@H]1CC[C@H]2C3=CC[…`
CHEMBL4164005 ChEMBL	Q15392	8.48 ~3.3 nM	374.6 Da LogP 5.13 TPSA 46.5	1 viol.	✓ Clean	`CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C…`
CHEMBL4167637 ChEMBL	Q15392	8.38 ~4.2 nM	402.6 Da LogP 5.31 TPSA 52.6	1 viol.	✓ Clean	`CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C…`
9W6 ChEMBL	A0R607	8.28 ~5.2 nM	376.4 Da LogP 2.89 TPSA 110.3	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1ccsc1NC(=O)c2nc3cnccc3s2`
CHEMBL4159728 ChEMBL	Q15392	8.26 ~5.5 nM	459.7 Da LogP 5.24 TPSA 55.8	1 viol.	✓ Clean	`CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C…`
CHEMBL4164428 ChEMBL	Q15392	8.20 ~6.3 nM	442.6 Da LogP 6.25 TPSA 52.6	1 viol.	✓ Clean	`C/C=C/C(=O)OC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4…`
CHEMBL3330226 ChEMBL	P9WJF1	8.00 ~10.0 nM	456.5 Da LogP 4.29 TPSA 79.6	✓ Ro5	✓ Clean	`O=c1nc(N2CCN(CC3CCCCC3)CC2)sc2c([N+](=O)[O-])cc…`
CHEMBL5180878 ChEMBL	P9WJF1	8.00 ~10.0 nM	401.5 Da LogP 3.89 TPSA 97.4	✓ Ro5	✓ Clean	`O=C(NC(=O)c1ccsc1NC(=O)c1nc2ccccc2s1)OCC1CC1`
CHEMBL5564800 ChEMBL	P9WJF1	7.75 ~17.8 nM	425.4 Da LogP 4.60 TPSA 76.3	✓ Ro5	✓ Clean	`CN(CC#CC1CCCCC1)c1nc(=O)c2cc(C(F)(F)F)cc([N+](=…`
CHEMBL4453252 ChEMBL	P9WJF1	7.52 ~30.2 nM	379.4 Da LogP 2.39 TPSA 114.2	✓ Ro5	✓ Clean	`Cc1ccnc(NC(=O)c2ccsc2NC(=O)c2ccn3cnnc3c2)n1`
38C ChEMBL	P9WJF1	7.39 ~40.7 nM	377.3 Da LogP 3.97 TPSA 84.3	✓ Ro5	✓ Clean	`COc1ccc(cc1)CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O`
CHEMBL4868912 ChEMBL	P9WJF1	7.30 ~50.1 nM	466.6 Da LogP 2.67 TPSA 113.7	✓ Ro5	✓ Clean	`CS(=O)(=O)c1cc([N+](=O)[O-])c2sc(N3CCN(CC4CCCCC…`
RG2 ChEMBL	P9WJF1	7.30 ~50.1 nM	381.7 Da LogP 4.61 TPSA 75.1	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)Cl`
1W6 ChEMBL	P9WJF1	7.28 ~52.5 nM	375.4 Da LogP 3.50 TPSA 97.4	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1ccsc1NC(=O)c2nc3ccccc3s2`
CHEMBL4475286 ChEMBL	P9WJF1	7.22 ~60.3 nM	359.4 Da LogP 1.93 TPSA 114.7	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1ccsc1NC(=O)c1ccn2cnnc2c1`
R26 ChEMBL	P9WJF1	7.17 ~67.6 nM	372.3 Da LogP 3.83 TPSA 98.9	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)C#N`
36C ChEMBL	P9WJF1	7.14 ~72.4 nM	365.3 Da LogP 4.10 TPSA 75.1	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)F`
R57 ChEMBL	P9WJF1	7.10 ~79.4 nM	395.3 Da LogP 4.11 TPSA 84.3	✓ Ro5	✓ Clean	`COc1ccc(cc1F)CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O`
R58 ChEMBL	P9WJF1	7.06 ~87.1 nM	391.3 Da LogP 4.36 TPSA 84.3	✓ Ro5	✓ Clean	`CCOc1ccc(cc1)CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O`
CHEMBL5197700 ChEMBL	P9WJF1	7.01 ~97.7 nM	415.5 Da LogP 4.28 TPSA 97.4	✓ Ro5	✓ Clean	`O=C(NC(=O)c1ccsc1NC(=O)c1nc2ccccc2s1)OCC1CCC1`
9W6 ChEMBL	P9WJF1	7.00 ~100.0 nM	376.4 Da LogP 2.89 TPSA 110.3	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1ccsc1NC(=O)c2nc3cnccc3s2`
Y22 ChEMBL	P9WJF1	6.92 ~120.2 nM	415.3 Da LogP 4.98 TPSA 75.1	✓ Ro5	✓ Clean	`c1cc(ccc1CNc2c(nc3ccc(cc3n2)C(F)(F)F)C(=O)O)C(F…`
CHEMBL4752208 ChEMBL	P9WJF1	6.85 ~141.3 nM	493.6 Da LogP 3.90 TPSA 62.7	✓ Ro5	✓ Clean	`COC(=O)C#Cc1cc(C(F)(F)F)cc2c(=O)nc(N3CCN(CC4CCC…`
CHEMBL4167452 ChEMBL	Q15392	6.70 ~199.5 nM	373.6 Da LogP 5.09 TPSA 52.3	1 viol.	✓ Clean	`CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC=C3[C@@H]2CC[C…`
CHEMBL4763381 ChEMBL	P9WJF1	6.70 ~199.5 nM	480.6 Da LogP 3.88 TPSA 79.5	✓ Ro5	✓ Clean	`NC(=O)/C=C/c1cc(C(F)(F)F)cc2c(=O)nc(N3CCN(CC4CC…`
CHEMBL4172305 ChEMBL	Q15392	6.69 ~204.2 nM	456.7 Da LogP 6.64 TPSA 52.6	1 viol.	✓ Clean	`C/C=C(\C)C(=O)OC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@…`
CHEMBL4740005 ChEMBL	P9WJF1	6.41 ~389.0 nM	494.6 Da LogP 4.14 TPSA 65.5	✓ Ro5	✓ Clean	`CNC(=O)/C=C/c1cc(C(F)(F)F)cc2c(=O)nc(N3CCN(CC4C…`
C6F ChEMBL	Q15392	6.37 ~426.6 nM	552.7 Da LogP 2.70 TPSA 121.1	1 viol.	Alert	`CCc1c(nc(c(n1)C(=O)N)Nc2ccc(c(c2)OC)N3CCC(CC3)N…`
CHEMBL4173086 ChEMBL	Q15392	6.09 ~812.8 nM	417.6 Da LogP 4.81 TPSA 64.6	✓ Ro5	✓ Clean	`CONC(=O)[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@…`
CHEMBL4162816 ChEMBL	Q15392	6.08 ~831.8 nM	401.6 Da LogP 4.88 TPSA 55.4	✓ Ro5	✓ Clean	`CNC(=O)[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H…`
CHEMBL4798070 ChEMBL	P9WJF1	6.04 ~912.0 nM	445.9 Da LogP 5.03 TPSA 36.4	1 viol.	✓ Clean	`O=c1nc(N2CCN(CC3CCCCC3)CC2)sc2c(Cl)cc(C(F)(F)F)…`
29S ChEMBL	Q15392	—	470.6 Da LogP 6.33 TPSA 57.9	1 viol.	✓ Clean	`Cc1c2cc(ccc2n(c1c3ccc(cc3)O)Cc4ccc(cc4)OCCN5CCC…`
CHEMBL1358 ChEMBL	Q15392	—	606.8 Da LogP 8.68 TPSA 63.5	2 viol.	✓ Clean	`C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCCCCC[S+…`
CHEMBL1655 ChEMBL	Q15392	—	406.0 Da LogP 6.22 TPSA 12.5	1 viol.	✓ Clean	`CN(C)CCOc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccccc2)cc1`
CHEMBL1822872 ChEMBL	A0R607	—	431.4 Da LogP 3.32 TPSA 94.8	✓ Ro5	✓ Clean	`C[C@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc([N+](=…`
CHEMBL1822872 ChEMBL	P9WJF1	—	431.4 Da LogP 3.32 TPSA 94.8	✓ Ro5	✓ Clean	`C[C@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc([N+](=…`
CHEMBL187709 ChEMBL	Q15392	—	438.0 Da LogP 5.85 TPSA 32.7	1 viol.	✓ Clean	`CCN(CC)CCOc1ccc(C(O)(Cc2ccc(Cl)cc2)c2ccc(C)cc2)…`
CHEMBL2355051 ChEMBL	Q15392	—	406.0 Da LogP 6.56 TPSA 12.5	1 viol.	✓ Clean	`CCN(CC)CCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1`
CHEMBL301327 ChEMBL	Q15392	—	457.6 Da LogP 6.26 TPSA 30.9	1 viol.	✓ Clean	`COc1ccc2c(c1)OC(C)(C)[C@@H](c1ccccc1)[C@@H]2c1c…`
CHEMBL3805705 ChEMBL	P9WJF1	—	427.4 Da LogP 4.35 TPSA 100.4	✓ Ro5	Alert	`C[C@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc(N=[N+]…`
CHEMBL4466845 ChEMBL	P9WJF1	—	433.4 Da LogP 3.32 TPSA 94.8	✓ Ro5	✓ Clean	`[2H]c1c(C(F)(F)F)c([2H])c2c(=O)nc(N3CCC4(CC3)OC…`
CHEMBL4514573 ChEMBL	A0R607	—	470.5 Da LogP 6.21 TPSA 73.8	1 viol.	✓ Clean	`O=[N+]([O-])c1cc(-c2nnc(SCc3ccccc3)n2Cc2ccccc2)…`
CHEMBL4514573 ChEMBL	P9WJF1	—	470.5 Da LogP 6.21 TPSA 73.8	1 viol.	✓ Clean	`O=[N+]([O-])c1cc(-c2nnc(SCc3ccccc3)n2Cc2ccccc2)…`
CHEMBL4563407 ChEMBL	O00116	—	345.3 Da LogP 2.94 TPSA 77.8	✓ Ro5	✓ Clean	`CC(CC(=O)NCc1ccc2[nH]c(=O)[nH]c2c1)c1c(F)cccc1F`
CHEMBL4745608 ChEMBL	P9WJF1	—	447.4 Da LogP 2.83 TPSA 108.8	✓ Ro5	✓ Clean	`C[C@H]1COC2(CCN(C(=O)c3sc4c([N+](=O)[O-])cc(C(F…`
CHEMBL4752738 ChEMBL	P9WJF1	—	411.4 Da LogP 4.16 TPSA 94.4	✓ Ro5	✓ Clean	`COc1ccc(CNC(=O)c2nc3cc(C(F)(F)F)cc([N+](=O)[O-]…`
CHEMBL4764258 ChEMBL	P9WJF1	—	495.6 Da LogP 4.56 TPSA 62.7	✓ Ro5	✓ Clean	`COC(=O)/C=C/c1cc(C(F)(F)F)cc2c(=O)nc(N3CCN(CC4C…`
CHEMBL4787991 ChEMBL	P9WJF1	—	490.4 Da LogP 5.14 TPSA 36.4	1 viol.	✓ Clean	`O=c1nc(N2CCN(CC3CCCCC3)CC2)sc2c(Br)cc(C(F)(F)F)…`
CTX ChEMBL	Q15392	—	371.5 Da LogP 6.00 TPSA 12.5	1 viol.	✓ Clean	`CC/C(=C(\c1ccccc1)/c2ccc(cc2)OCCN(C)C)/c3ccccc3`
RAL ChEMBL	Q15392	—	473.6 Da LogP 6.08 TPSA 70.0	1 viol.	✓ Clean	`c1cc(ccc1c2c(c3ccc(cc3s2)O)C(=O)c4ccc(cc4)OCCN5…`

Ligand	Tanimoto	MW · LogP · TPSA	Lipinski	PAINS	SMILES
ZINC141433347 ZINC	1.000	456.5 Da LogP 4.29 TPSA 79.6	✓ Ro5	✓ Clean	`O=c1nc(N2CCN(CC3CCCCC3)CC2)sc2c([N+](=O)[O-])cc…`
ZINC1644076 ZINC	1.000	214.4 Da LogP 4.68 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCCCCCCCCO`
ZINC1644076 ZINC	1.000	214.4 Da LogP 4.68 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCCCCCCCCO`
ZINC1680803 ZINC	1.000	200.4 Da LogP 4.29 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCCCCCCCO`
ZINC1680803 ZINC	1.000	200.4 Da LogP 4.29 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCCCCCCCO`
ZINC1850497 ZINC	1.000	220.4 Da LogP 4.69 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCCCc1ccc(O)cc1`
ZINC2039235 ZINC	1.000	206.3 Da LogP 4.30 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCCCCc1ccc(O)cc1`
ZINC239229132 ZINC	1.000	811.9 Da LogP 3.16 TPSA 217.0	2 viol.	Alert	`CC[C@]1(O)C[C@H](O[C@@H]2C[C@H](N(C)C)[C@H](O[C…`
ZINC239229133 ZINC	1.000	811.9 Da LogP 3.16 TPSA 217.0	2 viol.	Alert	`CC[C@]1(O)C[C@H](O[C@@H]2C[C@H](N(C)C)[C@H](O[C…`
ZINC239229134 ZINC	1.000	811.9 Da LogP 3.16 TPSA 217.0	2 viol.	Alert	`CC[C@]1(O)C[C@H](O[C@@H]2C[C@H](N(C)C)[C@H](O[C…`
ZINC28465419 ZINC	1.000	327.4 Da LogP 2.77 TPSA 62.2	✓ Ro5	Alert	`COc1cc2c(cc1O)[C@@H]1Cc3ccc(OC)c(O)c3CN1CC2`
ZINC28465423 ZINC	1.000	327.4 Da LogP 2.77 TPSA 62.2	✓ Ro5	Alert	`COc1cc2c(cc1O)[C@H]1Cc3ccc(OC)c(O)c3CN1CC2`
ZINC402792 ZINC	1.000	247.7 Da LogP 3.38 TPSA 54.0	✓ Ro5	✓ Clean	`O=C(Nc1ccccc1)Nc1ccnc(Cl)c1`
ZINC4275787 ZINC	1.000	375.4 Da LogP 3.50 TPSA 97.4	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1ccsc1NC(=O)c1nc2ccccc2s1`
ZINC43208590 ZINC	1.000	431.4 Da LogP 3.32 TPSA 94.8	✓ Ro5	✓ Clean	`C[C@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc([N+](=…`
ZINC43208590 ZINC	1.000	431.4 Da LogP 3.32 TPSA 94.8	✓ Ro5	✓ Clean	`C[C@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc([N+](=…`
ZINC5650743 ZINC	1.000	222.3 Da LogP 0.07 TPSA 57.2	✓ Ro5	✓ Clean	`CCOCCOCCOCCOCCO`
ZINC6403917 ZINC	1.000	354.4 Da LogP 0.11 TPSA 84.8	✓ Ro5	✓ Clean	`CCOCCOCCOCCOCCOCCOCCOCCO`
ZINC653884573 ZINC	1.000	427.4 Da LogP 4.35 TPSA 100.4	✓ Ro5	Alert	`C[C@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc(N=[N+]…`
ZINC69435448 ZINC	1.000	341.4 Da LogP 3.37 TPSA 77.8	✓ Ro5	✓ Clean	`C[C@@H](CC(=O)N[C@@H](C)c1ccc2[nH]c(=O)[nH]c2c1…`
ZINC69435452 ZINC	1.000	341.4 Da LogP 3.37 TPSA 77.8	✓ Ro5	✓ Clean	`C[C@H](NC(=O)C[C@@H](C)c1ccccc1F)c1ccc2[nH]c(=O…`
ZINC69435458 ZINC	1.000	341.4 Da LogP 3.37 TPSA 77.8	✓ Ro5	✓ Clean	`C[C@@H](CC(=O)N[C@H](C)c1ccc2[nH]c(=O)[nH]c2c1)…`
ZINC69435460 ZINC	1.000	341.4 Da LogP 3.37 TPSA 77.8	✓ Ro5	✓ Clean	`C[C@H](CC(=O)N[C@H](C)c1ccc2[nH]c(=O)[nH]c2c1)c…`
ZINC70466414 ZINC	1.000	431.4 Da LogP 3.32 TPSA 94.8	✓ Ro5	✓ Clean	`C[C@@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc([N+](…`
ZINC70466414 ZINC	1.000	431.4 Da LogP 3.32 TPSA 94.8	✓ Ro5	✓ Clean	`C[C@@H]1COC2(CCN(c3nc(=O)c4cc(C(F)(F)F)cc([N+](…`
ZINC31997771 ZINC	0.867	341.4 Da LogP 3.07 TPSA 51.2	✓ Ro5	Alert	`COc1cc2c(cc1OC)[C@@H]1Cc3ccc(OC)c(O)c3CN1CC2`
ZINC31997773 ZINC	0.867	341.4 Da LogP 3.07 TPSA 51.2	✓ Ro5	Alert	`COc1cc2c(cc1OC)[C@H]1Cc3ccc(OC)c(O)c3CN1CC2`
ZINC13840578 ZINC	0.842	238.2 Da LogP 4.08 TPSA 20.2	✓ Ro5	✓ Clean	`Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1`
ZINC26893796 ZINC	0.840	240.3 Da LogP 4.79 TPSA 20.2	✓ Ro5	✓ Clean	`CCCCCc1ccc(-c2ccc(O)cc2)cc1`
ZINC3269660 ZINC	0.824	254.2 Da LogP 2.45 TPSA 71.4	✓ Ro5	Alert	`O=C(O)c1ccc(C(=O)C(=O)c2ccccc2)cc1`
ZINC4275707 ZINC	0.824	332.4 Da LogP 3.79 TPSA 68.3	✓ Ro5	✓ Clean	`CCOC(=O)c1ccsc1NC(=O)c1nc2ccccc2s1`
ZINC185070 ZINC	0.815	272.3 Da LogP 3.29 TPSA 58.9	✓ Ro5	✓ Clean	`COc1cc(/C=C/c2ccc(O)c(OC)c2)ccc1O`
ZINC30725153 ZINC	0.813	341.4 Da LogP 3.07 TPSA 51.2	✓ Ro5	✓ Clean	`COc1cc2c(cc1O)[C@@H]1Cc3ccc(OC)c(OC)c3CN1CC2`
ZINC1651376 ZINC	0.809	365.3 Da LogP 4.10 TPSA 75.1	✓ Ro5	✓ Clean	`O=C(O)c1nc2ccc(C(F)(F)F)cc2nc1NCc1ccc(F)cc1`
ZINC118926312 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C…`
ZINC118926317 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C…`
ZINC2382312726 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C…`
ZINC2382312727 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C…`
ZINC253595413 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@@H]3[C@H](CC=C4C[C@@H](O)CC[C@@]43C…`
ZINC253595414 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@H](O)CC1=CC[C@H]1[C@H]2CC[C@@]2(C)[…`
ZINC253595415 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@@H]3[C@H](CC=C4C[C@@H](O)CC[C@@]43C…`
ZINC253595416 ZINC	0.800	334.5 Da LogP 3.28 TPSA 60.7	✓ Ro5	✓ Clean	`C[C@]12CC[C@H](O)CC1=CC[C@H]1[C@H]2CC[C@@]2(C)[…`
ZINC4275787 ZINC	0.796	375.4 Da LogP 3.50 TPSA 97.4	✓ Ro5	✓ Clean	`CCOC(=O)NC(=O)c1ccsc1NC(=O)c1nc2ccccc2s1`
ZINC2539409 ZINC	0.791	315.3 Da LogP 2.99 TPSA 115.4	✓ Ro5	✓ Clean	`C[C@@H](NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-]…`
ZINC2597086 ZINC	0.791	315.3 Da LogP 2.99 TPSA 115.4	✓ Ro5	✓ Clean	`C[C@H](NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])…`
ZINC22061234 ZINC	0.786	387.5 Da LogP 4.97 TPSA 32.7	✓ Ro5	✓ Clean	`CN(C)CCOc1ccc(/C(=C(\CCO)c2ccccc2)c2ccccc2)cc1`
ZINC2504355 ZINC	0.778	226.2 Da LogP 2.62 TPSA 54.4	✓ Ro5	✓ Clean	`O=C(O)c1ccc(C(=O)c2ccccc2)cc1`
ZINC22066525 ZINC	0.776	327.4 Da LogP 2.77 TPSA 62.2	✓ Ro5	✓ Clean	`COc1cc2c(cc1O)[C@H]1Cc3ccc(O)c(OC)c3CN1CC2`
ZINC22066528 ZINC	0.776	327.4 Da LogP 2.77 TPSA 62.2	✓ Ro5	✓ Clean	`COc1cc2c(cc1O)[C@@H]1Cc3ccc(O)c(OC)c3CN1CC2`
ZINC6037028 ZINC	0.776	318.5 Da LogP 4.31 TPSA 40.5	✓ Ro5	✓ Clean	`C[C@@H](O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)C…`

Cross-references

External database identifiers grouped by category.

Structure

AlphaFoldDBO00116
SMRO00116

Family & domains

Gene3D3.30.160.650
Gene3D3.30.300.330
Gene3D3.30.465.10
Gene3D3.30.70.3450
Gene3D3.30.43.10
Gene3D1.10.45.10
InterProIPR025650
InterProIPR004113
InterProIPR016166
InterProIPR036318
InterProIPR016167
InterProIPR016169
InterProIPR016164
InterProIPR006094
InterProIPR016171
PANTHERPTHR46568
PANTHERPTHR46568:SF1
PfamPF02913
PfamPF01565
SUPFAMSSF56176
SUPFAMSSF55103
PROSITEPS51387

Sequence

EMBLY09443
EMBLAY544121
EMBLAK314259
EMBLBC141820
CCDSCCDS2275.1
RefSeqNP_003650.1

Genome annotation

EnsemblENST00000264167.11
GeneID8540
KEGGhsa:8540
MANE-SelectENST00000264167.11
UCSCuc002ull.3
GenomeRNAi8540

Organism databases

CTD8540
DisGeNET8540
GeneCardsAGPS
HGNCHGNC:327
MIM600121
MIM603051

Expression

BgeeENSG00000018510
ExpressionAtlasO00116

Phylogenomics

eggNOGKOG1233
GeneTreeENSGT00940000156112
HOGENOMCLU_017779_2_2_1
InParanoidO00116
OMAGTISHQH
OrthoDB7786253at2759
PhylomeDBO00116

Proteomic

jPOSTO00116
MassIVEO00116
PaxDb9606-ENSP00000264167
ProteomicsDB47718

Other

BioGRID114110
CORUMO00116
FunCoupO00116
IntActO00116
MINTO00116
STRING9606.ENSP00000264167
ChEMBLCHEMBL4295643
SwissLipidsSLP:000000611
GlyGenO00116
iPTMnetO00116
MetOSiteO00116
PhosphoSitePlusO00116
SwissPalmO00116
BioMutaAGPS
PeptideAtlasO00116
PumbaO00116
Antibodypedia33922
DNASU8540
AGRHGNC:327
ClinPGxPA24624
HPAENSG00000018510
MalaCardsAGPS
OpenTargetsENSG00000018510
Orphanet309803
VEuPathDBHostDB:ENSG00000018510
PAN-GOO00116
BioCycMetaCyc:HS00389-MONOMER
BRENDA2.5.1.26
PathwayCommonsO00116
ReactomeR-HSA-75896
ReactomeR-HSA-9033241
ReactomeR-HSA-9033500
SignaLinkO00116
UniPathwayUPA00781
AgoraENSG00000018510
BioGRID-ORCS8540
ChiTaRSAGPS
PharosO00116
PROPR:O00116
ProteomesUP000005640
RNActO00116
GOGO:0005829
GOGO:0016020
GOGO:0005739
GOGO:0005782
GOGO:0005778
GOGO:0005777
GOGO:0008609
GOGO:0071949
GOGO:0008611
GOGO:0008610
FunFam1.10.45.10:FF:000002
FunFam3.30.160.650:FF:000001
FunFam3.30.300.330:FF:000001
FunFam3.30.43.10:FF:000003
FunFam3.30.465.10:FF:000011
FunFam3.30.70.3450:FF:000001