Length
189 aa
Mass
21,198 Da
Annotation score
5/5
Entry version
146
Overview
In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin
Publications
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
- Complete sequencing and characterization of 21,243 full-length human cDNAs.
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
- Elevated expression of TMEM205, a hypothetical membrane protein, is associated with cisplatin resistance.
- Initial characterization of the human central proteome.
- An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
- N-terminome analysis of the human mitochondrial proteome.
Function
Molecular function, catalytic activity, and Gene Ontology annotations.
0 EC
1 GO
In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin
Cellular component
membrane
Sequence
189 amino acids
MEEGGNLGGLIKMVHLLVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHAWAQLTFWEASQLYLLFLSLTLATVNARWLEPRTTAAMWALQTVEKERGLGGEVPGSHQGPDPYRQLREKDPKYSALRQNFFRYHGLSSLCNLGCVLSNGLCLAGLALEIRSL
Chain
1–189
Transmembrane protein 205
Cross-references
External database identifiers grouped by category.
Structure
- AlphaFoldDBQ6UW68
Family & domains
- InterProIPR042623
- InterProIPR025423
- PANTHERPTHR46916
- PANTHERPTHR46916:SF2
- PfamPF13664
Sequence
- EMBLAY358949
- EMBLAK291979
- EMBLCH471106
- EMBLBC064948
- EMBLBC091472
- CCDSCCDS32909.1
- RefSeqNP_001138888.1
- RefSeqNP_001308041.1
- RefSeqNP_001308042.1
- RefSeqNP_001308043.1
- RefSeqNP_212133.1
- RefSeqNP_940938.1
- RefSeqXP_005259956.1
- RefSeqXP_024307268.1
- RefSeqXP_024307269.1
- RefSeqXP_054176889.1
- RefSeqXP_054176890.1
Genome annotation
- EnsemblENST00000354882.10
- EnsemblENST00000447337.5
- EnsemblENST00000586590.5
- EnsemblENST00000586956.5
- EnsemblENST00000587948.5
- EnsemblENST00000588560.5
- EnsemblENST00000589555.5
- EnsemblENST00000593256.6
- GeneID374882
- KEGGhsa:374882
- MANE-SelectENST00000354882.10
- UCSCuc002mqz.3
- GenomeRNAi374882
Organism databases
- CTD374882
- DisGeNET374882
- GeneCardsTMEM205
- HGNCHGNC:29631
- MIM613771
Expression
- BgeeENSG00000105518
- ExpressionAtlasQ6UW68
Phylogenomics
- eggNOGKOG2886
- GeneTreeENSGT00390000016298
- InParanoidQ6UW68
- OMAFQMRAVE
- OrthoDB1641132at2759
- PhylomeDBQ6UW68
Proteomic
- jPOSTQ6UW68
- MassIVEQ6UW68
- PaxDb9606-ENSP00000346954
- ProteomicsDB67453
Other
- BioGRID131930
- FunCoupQ6UW68
- IntActQ6UW68
- MINTQ6UW68
- STRING9606.ENSP00000346954
- TCDB9.A.55.1.1
- iPTMnetQ6UW68
- PhosphoSitePlusQ6UW68
- SwissPalmQ6UW68
- BioMutaTMEM205
- DMDM74749383
- PeptideAtlasQ6UW68
- PumbaQ6UW68
- TopDownProteomicsQ6UW68
- Antibodypedia52091
- DNASU374882
- AGRHGNC:29631
- ClinPGxPA162406385
- HPAENSG00000105518
- OpenTargetsENSG00000105518
- VEuPathDBHostDB:ENSG00000105518
- PAN-GOQ6UW68
- PathwayCommonsQ6UW68
- SignaLinkQ6UW68
- AgoraENSG00000105518
- BioGRID-ORCS374882
- ChiTaRSTMEM205
- PharosQ6UW68
- PROPR:Q6UW68
- ProteomesUP000005640
- RNActQ6UW68
- GOGO:0016020