Human curated protein

Q8NG11

Tetraspanin-14

Gene: TSPAN14 Organism: Homo sapiens Reviewed UniProt

All human targets

Length 270 aa

Mass 30,691 Da

Annotation score 5/5

Entry version 167

Ligand records 73

Overview

Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10.

Subunit structure

Interacts with ADAM10; the interaction promotes ADAM10 maturation and cell surface expression

Publications

Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
The DNA sequence and comparative analysis of human chromosome 10.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Initial characterization of the human central proteome.
The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression.
TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization.
TspanC8 tetraspanins and A disintegrin and metalloprotease 10 (ADAM10) interact via their extracellular regions: evidence for distinct binding mechanisms for different TspanC8 proteins.

Identifiers

Gene: TSPAN14
UniProt: Q8NG11
Organism: Homo sapiens (taxon 9606)

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Subcellular location

Cell membrane

Keywords

Alternative splicing Cell membrane Disulfide bond Glycoprotein Membrane Proteomics identification Reference proteome Transmembrane Transmembrane helix

Function

Molecular function, catalytic activity, and Gene Ontology annotations.

0 EC 6 GO

Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates (PubMed:23035126, PubMed:26668317, PubMed:26686862, PubMed:37516108). Negatively regulates ADAM10-mediated cleavage of GP6 (By similarity). Promotes ADAM10-mediated cleavage of CDH5 (By similarity)

Biological process

positive regulation of Notch signaling pathway protein localization to plasma membrane protein maturation

Cellular component

cell surface endoplasmic reticulum lumen plasma membrane specific granule membrane tertiary granule membrane tetraspanin-enriched microdomain

Molecular function

enzyme binding

Sequence

270 amino acids

MHYYRYSNAKVSCWYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF

Chain

1–270 Tetraspanin-14

Region

114–232 Necessary and sufficient for interaction with ADAM10

Disulfide bond

153–221 —

154–186 —

170–180 —

187–200 —

Ligand evidence

Ligands grouped by evidence source, via the same LigQ_2 pipeline used across Target.

73 records

Chemistry signal

Structural and bioactivity evidence are both available for this target.

Direct evidence 0 same-protein records

Transferred evidence 23 records from similar proteins

Structural ligands 3 0 loaded crystals

Measured bioactivity 20 direct and transferred ChEMBL records

Proposed compounds 50 similarity-based ZINC candidates

No co-crystallized ligand found for this exact protein.

Ligand	Source crystal	UniProt (homolog)	MW · LogP · TPSA	Lipinski	PAINS	SMILES
CLR RCSB PDB	5TCX	P60033	386.7 Da LogP 7.39 TPSA 20.2	1 viol.	✓ Clean	`CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3…`
OLC RCSB PDB	6K4J	P21926	356.5 Da LogP 4.92 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](CO)O`
PLM RCSB PDB	6K4J	P21926	256.4 Da LogP 5.55 TPSA 37.3	1 viol.	✓ Clean	`CCCCCCCCCCCCCCCC(=O)O`

No matches.

Ligand	UniProt (homolog)	pchembl	MW · LogP · TPSA	Lipinski	PAINS	SMILES
CHEMBL171331 ChEMBL	Q6RY99	8.48 ~3.3 nM	184.2 Da LogP 1.57 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)/C=C/C(O)C1CCCCC1`
CHEMBL354804 ChEMBL	Q6RY99	8.46 ~3.5 nM	124.1 Da LogP -4.71 TPSA 60.4	✓ Ro5	✓ Clean	`O=C([O-])/C=C/CO.[Na+]`
CHEMBL171595 ChEMBL	Q6RY99	7.96 ~11.0 nM	116.1 Da LogP 0.01 TPSA 57.5	✓ Ro5	✓ Clean	`CC(O)/C=C/C(=O)O`
CHEMBL464557 ChEMBL	P60033	7.68 ~20.9 nM	472.7 Da LogP 6.20 TPSA 77.8	1 viol.	✓ Clean	`CC1(C)CC[C@]2(C(=O)O)[C@H](O)C[C@]3(C)C(=CC[C@@…`
CHEMBL3953841 ChEMBL	P08962	7.48 ~33.1 nM	418.5 Da LogP 1.71 TPSA 126.7	✓ Ro5	Alert	`Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCO[C@@H](CO)C4)c…`
CHEMBL4546270 ChEMBL	P60033	7.42 ~38.0 nM	268.3 Da LogP 2.11 TPSA 91.7	✓ Ro5	✓ Clean	`CC(=O)[C@@H]1C[C@H](C(=O)O)[C@@]1(C)CC/C=C(\C)C…`
CHEMBL3917084 ChEMBL	P08962	7.29 ~51.3 nM	457.5 Da LogP 2.34 TPSA 109.7	✓ Ro5	Alert	`Cc1ncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)cc3…`
CHEMBL4446488 ChEMBL	P60033	7.18 ~66.1 nM	314.3 Da LogP 1.36 TPSA 132.1	✓ Ro5	✓ Clean	`C/C(=C\CC[C@]1(C)[C@@H](C(=O)O)C[C@H]1[C@](C)(O…`
R6D ChEMBL	P08962	7.10 ~79.4 nM	443.5 Da LogP 2.03 TPSA 109.7	✓ Ro5	Alert	`c1cc(ccc1Nc2c3nccn3cc(n2)c4cncc(n4)N)N5CCN(CC5)…`
CHEMBL5083772 ChEMBL	P08962	7.09 ~81.3 nM	542.6 Da LogP 3.04 TPSA 127.9	2 viol.	✓ Clean	`Cn1cc(Nc2nccc(-c3ccc4c(c3)CN(C3COC3)CC[C@H]4NC(…`
CHEMBL3978560 ChEMBL	P08962	7.00 ~100.0 nM	387.4 Da LogP 2.95 TPSA 93.6	✓ Ro5	Alert	`Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCOCC4)cc3)n2)c1`
CHEMBL3902654 ChEMBL	P08962	6.92 ~120.2 nM	503.6 Da LogP 1.40 TPSA 139.2	2 viol.	Alert	`Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)c(…`
CHEMBL3973635 ChEMBL	P08962	6.89 ~128.8 nM	475.6 Da LogP 1.23 TPSA 141.0	1 viol.	Alert	`Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(CC(CO)CO)CC4)…`
CHEMBL3929647 ChEMBL	P08962	6.80 ~158.5 nM	457.5 Da LogP 2.34 TPSA 109.7	✓ Ro5	Alert	`Cc1c(-c2cncc(N)n2)nc(Nc2ccc(N3CCN(C4COC4)CC3)cc…`
CHEMBL3911668 ChEMBL	P08962	6.78 ~166.0 nM	517.6 Da LogP 1.71 TPSA 139.2	2 viol.	Alert	`Cc1ncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)c(O…`
CHEMBL3952825 ChEMBL	P08962	6.60 ~251.2 nM	401.5 Da LogP 3.26 TPSA 93.6	✓ Ro5	Alert	`Cc1ncc(-c2cn3ccnc3c(Nc3ccc(N4CCOCC4)cc3)n2)cc1N`
CHEMBL514926 ChEMBL	Q6RY99	6.40 ~398.1 nM	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)/C=C1\CCCc2ccccc2[C@@H]1O`
CHEMBL472694 ChEMBL	Q6RY99	6.30 ~501.2 nM	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)/C=C1\CCCc2ccccc2C1O`
CHEMBL3962740 ChEMBL	P08962	6.13 ~741.3 nM	362.4 Da LogP 3.13 TPSA 99.6	✓ Ro5	✓ Clean	`COc1ccc(Nc2nc(-c3ccc(N)nc3)cn3ccnc23)cc1OC`
CHEMBL3981576 ChEMBL	P08962	6.09 ~812.8 nM	361.4 Da LogP 3.74 TPSA 86.7	✓ Ro5	✓ Clean	`COc1ccc(Nc2nc(-c3cccc(N)c3)cn3ccnc23)cc1OC`

Ligand	Tanimoto	MW · LogP · TPSA	Lipinski	PAINS	SMILES
ZINC1501016272 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCC/C=C\CCCCCCC(=O)OC[C@H](O)CO`
ZINC1501016273 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCC/C=C\CCCCCCC(=O)OC[C@@H](O)CO`
ZINC1501016315 ZINC	1.000	314.5 Da LogP 3.75 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC/C=C\CCCCCCC(=O)OC[C@@H](O)CO`
ZINC1501016316 ZINC	1.000	314.5 Da LogP 3.75 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC/C=C\CCCCCCC(=O)OC[C@H](O)CO`
ZINC1529498 ZINC	1.000	200.3 Da LogP 3.99 TPSA 37.3	✓ Ro5	✓ Clean	`CCCCCCCCCCCC(=O)O`
ZINC1530417 ZINC	1.000	228.4 Da LogP 4.77 TPSA 37.3	✓ Ro5	✓ Clean	`CCCCCCCCCCCCCC(=O)O`
ZINC1628119 ZINC	1.000	214.3 Da LogP 4.38 TPSA 37.3	✓ Ro5	✓ Clean	`CCCCCCCCCCCCC(=O)O`
ZINC1772617172 ZINC	1.000	443.5 Da LogP 2.03 TPSA 109.7	✓ Ro5	Alert	`Nc1cncc(-c2cn3ccnc3c(Nc3ccc(N4CCN(C5COC5)CC4)cc…`
ZINC2038077522 ZINC	1.000	356.5 Da LogP 4.92 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCCC=CCCCCCCCC(=O)OC[C@@H](O)CO`
ZINC2038077523 ZINC	1.000	356.5 Da LogP 4.92 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCCC=CCCCCCCCC(=O)OC[C@H](O)CO`
ZINC2055496722 ZINC	1.000	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)C=C1CCCc2ccccc2[C@@H]1O`
ZINC2055496723 ZINC	1.000	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)C=C1CCCc2ccccc2[C@H]1O`
ZINC221534416 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C\CCCCCC(=O)OC[C@@H](O)CO`
ZINC32840893 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CO`
ZINC32840894 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC/C=C/CCCCCCCC(=O)OC[C@@H](O)CO`
ZINC32840895 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC/C=C\CCCCCCCC(=O)OC[C@H](O)CO`
ZINC32840896 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC/C=C/CCCCCCCC(=O)OC[C@H](O)CO`
ZINC32840901 ZINC	1.000	356.5 Da LogP 4.92 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CO`
ZINC32840902 ZINC	1.000	356.5 Da LogP 4.92 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@@H](O)CO`
ZINC32840903 ZINC	1.000	356.5 Da LogP 4.92 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](O)CO`
ZINC32840904 ZINC	1.000	356.5 Da LogP 4.92 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C/CCCCCCCC(=O)OC[C@H](O)CO`
ZINC3782203 ZINC	1.000	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)/C=C1\CCCc2ccccc2[C@@H]1O`
ZINC3983943 ZINC	1.000	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)/C=C1\CCCc2ccccc2[C@H]1O`
ZINC6117211 ZINC	1.000	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)/C=C1/CCCc2ccccc2[C@H]1O`
ZINC6117212 ZINC	1.000	218.3 Da LogP 2.07 TPSA 57.5	✓ Ro5	✓ Clean	`O=C(O)/C=C1/CCCc2ccccc2[C@@H]1O`
ZINC725433050 ZINC	1.000	342.5 Da LogP 4.53 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C\CCCCCCC(=O)OC[C@@H](O)CO`
ZINC725433052 ZINC	1.000	342.5 Da LogP 4.53 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C\CCCCCCC(=O)OC[C@H](O)CO`
ZINC98208566 ZINC	1.000	328.5 Da LogP 4.14 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCCCC/C=C\CCCCCC(=O)OC[C@H](O)CO`
ZINC32840885 ZINC	0.943	300.4 Da LogP 3.36 TPSA 66.8	✓ Ro5	✓ Clean	`CCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CO`
ZINC2053467566 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC=CCC=CCCCCCCCC(=O)OC[C@@H](O)CO`
ZINC2053467567 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCCC=CCC=CCCCCCCCC(=O)OC[C@H](O)CO`
ZINC29045599 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCC/C=C/C/C=C\CCCCCCCC(=O)OC[C@H](O)CO`
ZINC4557100 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC[C@H](O)CO`
ZINC4557101 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC[C@@H](O)CO`
ZINC5819989 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCC/C=C/C/C=C/CCCCCCCC(=O)OC[C@H](O)CO`
ZINC5819990 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCC/C=C/C/C=C/CCCCCCCC(=O)OC[C@@H](O)CO`
ZINC85425978 ZINC	0.919	354.5 Da LogP 4.70 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCC/C=C\C/C=C/CCCCCCCC(=O)OC[C@H](O)CO`
ZINC29045446 ZINC	0.892	352.5 Da LogP 4.47 TPSA 66.8	✓ Ro5	✓ Clean	`CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)OC[C@@H](O)CO`
ZINC138457918 ZINC	0.850	228.3 Da LogP 3.56 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCCC(=O)CCCCC(=O)O`
ZINC144395054 ZINC	0.850	242.4 Da LogP 3.95 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCC(=O)CCCCCCCC(=O)O`
ZINC14619628 ZINC	0.850	270.4 Da LogP 4.73 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCC(=O)CCCCCCCCCC(=O)O`
ZINC196749828 ZINC	0.850	214.3 Da LogP 3.17 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCC(=O)CCCCC(=O)O`
ZINC2113934076 ZINC	0.850	256.4 Da LogP 4.34 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCC(=O)CCCCCCCC(=O)O`
ZINC2113934082 ZINC	0.850	256.4 Da LogP 4.34 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCCC(=O)CCCCCCC(=O)O`
ZINC2113934083 ZINC	0.850	256.4 Da LogP 4.34 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCCCCC(=O)CCCCC(=O)O`
ZINC4798470 ZINC	0.850	270.4 Da LogP 4.73 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCC(=O)CCCCCCCCC(=O)O`
ZINC71418182 ZINC	0.850	270.4 Da LogP 4.73 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCCCCCC(=O)CCCCC(=O)O`
ZINC79244776 ZINC	0.850	270.4 Da LogP 4.73 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCCC(=O)CCCCCCCC(=O)O`
ZINC86037082 ZINC	0.850	270.4 Da LogP 4.73 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCCCCC(=O)CCCCCC(=O)O`
ZINC86037089 ZINC	0.850	270.4 Da LogP 4.73 TPSA 54.4	✓ Ro5	✓ Clean	`CCCCCCCCC(=O)CCCCCCC(=O)O`

Cross-references

External database identifiers grouped by category.

Structure

AlphaFoldDBQ8NG11
SMRQ8NG11

Family & domains

CDDcd03159
Gene3D1.10.1450.10
InterProIPR018499
InterProIPR000301
InterProIPR018503
InterProIPR008952
PANTHERPTHR19282
PANTHERPTHR19282:SF261
PfamPF00335
PIRSFPIRSF002419
PRINTSPR00259
SUPFAMSSF48652
PROSITEPS00421

Sequence

EMBLAF311903
EMBLAL136638
EMBLAK295321
EMBLAC021028
EMBLCH471142
EMBLCH471142
EMBLCH471142
EMBLCH471142
EMBLCH471142
EMBLBC002920
EMBLBC093016
CCDSCCDS44448.1
CCDSCCDS7369.1
RefSeqNP_001121781.1
RefSeqNP_001338195.1
RefSeqNP_001338196.1
RefSeqNP_001338197.1
RefSeqNP_001338198.1
RefSeqNP_001338199.1
RefSeqNP_001338200.1
RefSeqNP_001338201.1
RefSeqNP_112189.2

Genome annotation

EnsemblENST00000372156.5
EnsemblENST00000372158.6
EnsemblENST00000372164.7
EnsemblENST00000429989.8
EnsemblENST00000481124.5
EnsemblENST00000714437.1
EnsemblENST00000714440.1
EnsemblENST00000714441.1
EnsemblENST00000714442.1
EnsemblENST00000714443.1
EnsemblENST00000714444.1
EnsemblENST00000714445.1
GeneID81619
KEGGhsa:81619
MANE-SelectENST00000429989.8
UCSCuc001kci.5
GenomeRNAi81619

Organism databases

CTD81619
DisGeNET81619
GeneCardsTSPAN14
HGNCHGNC:23303

Expression

BgeeENSG00000108219
ExpressionAtlasQ8NG11

Phylogenomics

eggNOGKOG3882
GeneTreeENSGT00940000159235
InParanoidQ8NG11
OMAQRMNHCC
OrthoDB2014092at2759
PhylomeDBQ8NG11

Proteomic

jPOSTQ8NG11
MassIVEQ8NG11
PaxDb9606-ENSP00000396270
ProteomicsDB73407
ProteomicsDB73408
ProteomicsDB73409

Other

BioGRID123554
FunCoupQ8NG11
IntActQ8NG11
MINTQ8NG11
STRING9606.ENSP00000361231
TCDB8.A.40.1.21
GlyCosmosQ8NG11
GlyGenQ8NG11
iPTMnetQ8NG11
PhosphoSitePlusQ8NG11
SwissPalmQ8NG11
BioMutaTSPAN14
DMDM55976537
CPTACCPTAC-1188
PeptideAtlasQ8NG11
PumbaQ8NG11
Antibodypedia3113
DNASU81619
AGRHGNC:23303
ClinPGxPA128394731
HPAENSG00000108219
NIAGADSENSG00000108219
OpenTargetsENSG00000108219
VEuPathDBHostDB:ENSG00000108219
PAN-GOQ8NG11
PathwayCommonsQ8NG11
ReactomeR-HSA-6798695
ReactomeR-HSA-977225
SignaLinkQ8NG11
AgoraENSG00000108219
BioGRID-ORCS81619
ChiTaRSTSPAN14
PharosQ8NG11
PROPR:Q8NG11
ProteomesUP000005640
RNActQ8NG11
GOGO:0009986
GOGO:0005788
GOGO:0005886
GOGO:0035579
GOGO:0070821
GOGO:0097197
GOGO:0019899
GOGO:0045747
GOGO:0072659
GOGO:0051604
FunFam1.10.1450.10:FF:000001