Protein profile

VK055_0024

yedD-like family protein

Genome: KpATCC43816

Gene: AIK78655.1 Structure source: Experimental + ColabFold UniProt A6TB72
Export view
Amino acids 143
Annotations 0
Features 11
PDB binders 0
Druggability 0.382

Overview

Basic information about this protein and its source genome.

Accession
VK055_0024
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK78655.1
Status
annotated
Amino acids
143
Structure source
Experimental + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
87.48

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.382
Structure 4HWM
Pocket Pocket 3
P2Rank 0.046
Structure 4HWM
Pocket Pocket 1
ColabFold model
FPocket 0.41 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 64 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
1 19 Phobius SIGNAL_PEPTIDE Signal peptide region
20 143 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 19 SignalP_EUK SignalP-noTM SignalP-noTM
1 16 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
25 130 Pfam PF13987 YedD-like protein
25 130 InterPro IPR025596 YedD-like protein
4 14 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
15 19 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
14 143 Gene3D G3DSA:2.40.128.500 -
14 143 InterPro IPR038624 YedD-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 4HWM
X-ray 20.00 Å - —
PDBe RCSB PDBj File
Viewing
ColabFold VK055_0024
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.382

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.07 0.046
2 1.28 0.013