Protein profile

VK055_0065

hypothetical protein

Genome: KpATCC43816

Gene: AIK78693.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GVH5
Export view
Amino acids 272
Annotations 0
Features 8
PDB binders 0
Druggability 0.556

Overview

Basic information about this protein and its source genome.

Accession
VK055_0065
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK78693.1
Status
annotated
Amino acids
272
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
93.5

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.556
Structure A0A0H3GVH5
Pocket Pocket 3
P2Rank 0.364
Structure A0A0H3GVH5
Pocket Pocket 1
ColabFold model
FPocket 0.441 · Pocket 2
P2Rank 0.36 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 90 / 4744 genomes with a hit
Normalized 0.019

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
21 248 Pfam PF01904 Protein of unknown function DUF72
21 248 InterPro IPR002763 Protein of unknown function DUF72
2 258 PANTHER PTHR30348 UNCHARACTERIZED PROTEIN YECE
2 258 InterPro IPR002763 Protein of unknown function DUF72
1 255 Gene3D G3DSA:3.20.20.410 Protein of unknown function UPF0759
1 255 InterPro IPR036520 UPF0759 superfamily
1 252 SUPERFAMILY SSF117396 TM1631-like
1 252 InterPro IPR036520 UPF0759 superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GVH5
AlphaFold — — full sequence — Viewing
ColabFold VK055_0065
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.556
2 0.005
1 0.002
17 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.09 0.364
2 1.46 0.016
3 1.3 0.012
4 1.1 0.007