Protein profile

VK055_0150

hypothetical protein

Genome: KpATCC43816

Gene: AIK78778.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GPY1
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Amino acids 479
Annotations 0
Features 8
PDB binders 0
Druggability 0.516

Overview

Basic information about this protein and its source genome.

Accession
VK055_0150
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK78778.1
Status
annotated
Amino acids
479
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
28.018
Localization
Cytoplasmic
ColabFold pLDDT
91.52

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.516
Structure A0A0H3GPY1
Pocket Pocket 31
P2Rank 0.876
Structure A0A0H3GPY1
Pocket Pocket 1
ColabFold model
FPocket 0.424 · Pocket 5
P2Rank 0.904 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 72 / 4744 genomes with a hit
Normalized 0.015

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
1 478 PIRSF PIRSF005522 UCP005522
1 478 InterPro IPR016450 Uncharacterised conserved protein UCP005522
348 407 Gene3D G3DSA:3.30.1490.270 -
78 451 Pfam PF14403 Circularly permuted ATP-grasp type 2
78 451 InterPro IPR025841 Circularly permuted ATP-grasp type 2
215 311 Gene3D G3DSA:3.40.50.11290 -
10 477 PANTHER PTHR34595 BLR5612 PROTEIN
20 466 SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GPY1
AlphaFold — — full sequence — Viewing
ColabFold VK055_0150
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.238
8 0.037
1 0.011
20 0.011

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 26.7 0.876
2 3.13 0.085
3 3.13 0.085
4 2.12 0.041
5 1.92 0.033