Protein profile

VK055_0264

hypothetical protein

Genome: KpATCC43816

Gene: AIK78890.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GRC5
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Amino acids 109
Annotations 0
Features 10
PDB binders 0
Druggability 0.373

Overview

Basic information about this protein and its source genome.

Accession
VK055_0264
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK78890.1
Status
annotated
Amino acids
109
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
44.66
DEG E-value
2.29e-28
Localization
Cytoplasmic
ColabFold pLDDT
89.25

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.373
Structure A0A0H3GRC5
Pocket Pocket 1
P2Rank 0.005
Structure A0A0H3GRC5
Pocket Pocket 1
ColabFold model
FPocket 0.262 · Pocket 3
P2Rank 0.047 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 102 / 4744 genomes with a hit
Normalized 0.022

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

10 records
Show feature table
Start End DB Term Name
1 109 PIRSF PIRSF004916 UCP004916
1 109 InterPro IPR007376 dsDNA mimic, putative
9 109 Gene3D G3DSA:3.10.450.140 dsDNA mimic, putative
9 109 InterPro IPR036763 Putative dsDNA mimic superfamily
5 109 Hamap MF_00680 UPF0263 protein YciU [yciU].
5 109 InterPro IPR007376 dsDNA mimic, putative
8 109 Pfam PF04269 Protein of unknown function, DUF440
8 109 InterPro IPR007376 dsDNA mimic, putative
3 109 SUPERFAMILY SSF102816 Putative dsDNA mimic
3 109 InterPro IPR036763 Putative dsDNA mimic superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GRC5
AlphaFold — — full sequence — Viewing
ColabFold VK055_0264
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.373
3 0.172
2 0.007
4 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.0 0.005