Protein profile

VK055_0521

hypothetical protein

Genome: KpATCC43816

Gene: AIK79144.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GQM1
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Amino acids 127
Annotations 1
Features 9
PDB binders 0
Druggability 0.472

Overview

Basic information about this protein and its source genome.

Accession
VK055_0521
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79144.1
Status
annotated
Amino acids
127
Structure source
AlphaFold + ColabFold
GO
GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
92.99

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.472
Structure A0A0H3GQM1
Pocket Pocket 7
P2Rank
Structure A0A0H3GQM1
Pocket No pockets
ColabFold model
FPocket 0.726 · Pocket 1
P2Rank 0.002 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 40 / 4744 genomes with a hit
Normalized 0.008

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
1 126 Gene3D G3DSA:1.10.10.10 -
1 126 InterPro IPR036388 Winged helix-like DNA-binding domain superfamily
1 119 PANTHER PTHR33204 TRANSCRIPTIONAL REGULATOR, MARR FAMILY
1 79 Pfam PF01638 HxlR-like helix-turn-helix
1 79 InterPro IPR002577 Helix-turn-helix, HxlR type
1 116 SUPERFAMILY SSF46785 Winged helix DNA-binding domain
1 116 InterPro IPR036390 Winged helix DNA-binding domain superfamily
1 82 ProSiteProfiles PS51118 HxlR-type HTH domain profile.
1 82 InterPro IPR002577 Helix-turn-helix, HxlR type

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GQM1
AlphaFold — — full sequence — Viewing
ColabFold VK055_0521
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
7 0.472
1 0.125
4 0.045
2 0.008