Protein profile

VK055_0902

hsp20/alpha crystallin family protein

Genome: KpATCC43816

Gene: AIK79525.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GX51
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Amino acids 157
Annotations 0
Features 16
PDB binders 0
Druggability 0.357

Overview

Basic information about this protein and its source genome.

Accession
VK055_0902
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79525.1
Status
annotated
Amino acids
157
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
71.35

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.357
Structure A0A0H3GX51
Pocket Pocket 4
P2Rank 0.025
Structure A0A0H3GX51
Pocket Pocket 1
ColabFold model
FPocket 0.611 · Pocket 12
P2Rank 0.243 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 18 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
1 4 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
39 148 Gene3D G3DSA:2.60.40.790 -
39 148 InterPro IPR008978 HSP20-like chaperone
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
5 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
16 146 SUPERFAMILY SSF49764 HSP20-like chaperones
16 146 InterPro IPR008978 HSP20-like chaperone
14 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
47 146 Pfam PF00011 Hsp20/alpha crystallin family
47 146 InterPro IPR002068 Alpha crystallin/Hsp20 domain
34 149 ProSiteProfiles PS01031 Small heat shock protein (sHSP) domain profile.
34 149 InterPro IPR002068 Alpha crystallin/Hsp20 domain
41 131 CDD cd06470 ACD_IbpA-B_like
41 131 InterPro IPR037913 Small heat shock protein IbpA/IbpB, ACD domain
19 157 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
4 156 PANTHER PTHR47062 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GX51
AlphaFold — — full sequence — Viewing
ColabFold VK055_0902
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.004
1 0.0
7 0.0
10 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.73 0.025
2 1.51 0.018