Protein profile

VK055_1121

hypothetical protein

Genome: KpATCC43816

Gene: AIK79744.1 Structure source: AlphaFold + ColabFold UniProt A0A422ZIF7
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Amino acids 464
Annotations 0
Features 9
PDB binders 0
Druggability 0.403

Overview

Basic information about this protein and its source genome.

Accession
VK055_1121
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79744.1
Status
annotated
Amino acids
464
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
92.04

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.403
Structure A0A422ZIF7
Pocket Pocket 20
P2Rank 0.964
Structure A0A422ZIF7
Pocket Pocket 1
ColabFold model
FPocket 0.458 · Pocket 25
P2Rank 0.952 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 21 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
24 27 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
5 24 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
52 233 Gene3D G3DSA:1.50.10.140 -
8 23 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
1 27 Phobius SIGNAL_PEPTIDE Signal peptide region
28 464 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
54 423 Pfam PF11329 Protein of unknown function (DUF3131)
54 423 InterPro IPR021478 Protein of unknown function DUF3131

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A422ZIF7
AlphaFold — — full sequence — Viewing
ColabFold VK055_1121
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
20 0.403
22 0.082
4 0.027
1 0.002

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 48.28 0.964
2 6.39 0.269
3 2.71 0.066
4 1.33 0.013
5 1.05 0.006