Protein profile

VK055_1122

hypothetical protein

Genome: KpATCC43816

Gene: AIK79745.1 Structure source: AlphaFold + ColabFold UniProt A0A1W2IZW3
Amino acids 144
Annotations 2
Features 4
PDB binders 0
Druggability 0.387

Overview

Basic information about this protein and its source genome.

Accession
VK055_1122
Gene
AIK79745.1
Status
annotated
Amino acids
144
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
80.71

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.387
Structure A0A1W2IZW3
Pocket Pocket 3
P2Rank 0.02
Structure A0A1W2IZW3
Pocket Pocket 1
ColabFold model
FPocket 0.613 · Pocket 2
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 17 / 4744 genomes with a hit
Normalized 0.004

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

2 GO

Gene Ontology (GO)

2
  • GO:0019825 Binding to oxygen (O2).
  • GO:0020037 Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
3 135 Gene3D G3DSA:1.10.490.10 Globins
3 135 InterPro IPR012292 Globin/Protoglobin
7 131 SUPERFAMILY SSF46458 Globin-like
7 131 InterPro IPR009050 Globin-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A1W2IZW3
AlphaFold full sequence Viewing
ColabFold VK055_1122
ColabFold full sequence Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.025
11 0.01
9 0.001
10 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.57 0.02