Protein profile

VK055_1222

ydjC-like family protein

Genome: KpATCC43816

Gene: AIK79845.1 Structure source: Experimental + ColabFold UniProt A6T7U7
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Amino acids 252
Annotations 3
Features 12
PDB binders 0
Druggability 0.809

Overview

Basic information about this protein and its source genome.

Accession
VK055_1222
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79845.1
Status
annotated
Amino acids
252
Structure source
Experimental + ColabFold
GO
GO:0016811 Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. GO:0005975 The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0000272 The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
28.956
Human E-value
5.36e-22
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
97.99

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.809
Structure 7VI8
Pocket Pocket 1
P2Rank 0.754
Structure 7VI8
Pocket Pocket 1
ColabFold model
FPocket 0.338 · Pocket 4
P2Rank 0.783 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 85 / 4744 genomes with a hit
Normalized 0.018

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

3 GO

Gene Ontology (GO)

3
  • GO:0016811 Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
  • GO:0005975 The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
  • GO:0000272 The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
5 236 CDD cd10803 YdjC_EF3048_like
5 236 InterPro IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria
5 240 Pfam PF04794 YdjC-like protein
5 240 InterPro IPR006879 Carbohydrate deacetylase YdjC-like
1 252 FunFam G3DSA:3.20.20.370:FF:000001 Chitooligosaccharide deacetylase
159 252 PANTHER PTHR31609 YDJC DEACETYLASE FAMILY MEMBER
159 252 InterPro IPR006879 Carbohydrate deacetylase YdjC-like
1 252 Gene3D G3DSA:3.20.20.370 Glycoside hydrolase/deacetylase
3 249 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG].
3 249 InterPro IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria
1 252 SUPERFAMILY SSF88713 Glycoside hydrolase/deacetylase
1 252 InterPro IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 7VI8
X-ray 20.00 Å - —
PDBe RCSB PDBj File
Viewing
ColabFold VK055_1222
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.809

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 15.48 0.754
2 13.95 0.705
3 2.54 0.072
4 1.39 0.017
5 1.27 0.013