Metabolic network

VK055_1266

scaffolding protein that interacts with murein polymerase and murein hydrolase

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Network centrality 0
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

No specific KEGG pathway assigned - this reaction either has no KEGG mapping, or only matches a generic overview map with no route-level information.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-25003

EC 3.5.1.28 · RXN-25003 · not reversible · 4 isoenzymes

a peptidoglycan 2 H2O
→
a denuded glycan 2 a peptidoglycan pentapeptide

RXN-24482[CCO-PERI-BAC]-CPD-12298/WATER//CPD-15797/CPD-27102.51.

EC 3.5.1.28 · RXN-24482[CCO-PERI-BAC]-CPD-12298/WATER//CPD-15797/CPD-27102.51. · not reversible · 4 isoenzymes

Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-iGln-L-Lys-D-Ala-D-Ala H2O
→
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramate L-alanyl-gamma-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine

RXN-24482[CCO-CYTOSOL]-CPD-12298/WATER//CPD-15797/CPD-27102.50.

EC 3.5.1.28 · RXN-24482[CCO-CYTOSOL]-CPD-12298/WATER//CPD-15797/CPD-27102.50. · not reversible · 4 isoenzymes

Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-iGln-L-Lys-D-Ala-D-Ala H2O
→
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramate L-alanyl-gamma-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine

RXN8J2-155

EC 3.5.1.28 · RXN8J2-155 · not reversible · 4 isoenzymes

Und-PP-[beta-D-GlcNAc-(1->4)]-MurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala-D-Ala H2O
→
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramate L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

RXN-22613[CCO-CYTOSOL]-CPD2DDB-21/WATER//CPD-15797/CPD-24852/PROTON.58.

EC 3.5.1.28 · RXN-22613[CCO-CYTOSOL]-CPD2DDB-21/WATER//CPD-15797/CPD-24852/PROTON.58. · not reversible · 4 isoenzymes

lipid II (L. plantarum) H2O
→
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramate L-alanyl-gamma-D-isoglutaminyl-amidated-meso-2,6-diaminopimeloyl-D-alanyl-D-lactate H+

RXN-22613[CCO-EXTRACELLULAR]-CPD2DDB-21/WATER//CPD-15797/CPD-24852/PROTON.64.

EC 3.5.1.28 · RXN-22613[CCO-EXTRACELLULAR]-CPD2DDB-21/WATER//CPD-15797/CPD-24852/PROTON.64. · not reversible · 4 isoenzymes

lipid II (L. plantarum) H2O
→
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramate L-alanyl-gamma-D-isoglutaminyl-amidated-meso-2,6-diaminopimeloyl-D-alanyl-D-lactate H+

RXN0-5225

EC 3.5.1.28 · RXN0-5225 · not reversible · 4 isoenzymes

Producing chokepoint
GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-meso-DAP-D-Ala H2O
→
N-acetyl-beta-D-glucosamine-1,6-anhydro-N-acetyl-beta-D-muramate L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

Imported from KpATCC43816.sbml · 2026-07-09