Protein profile

VK055_1288

hypothetical protein

Genome: KpATCC43816

Gene: AIK79912.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GRQ5
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Amino acids 79
Annotations 0
Features 11
PDB binders 0
Druggability 0.002

Overview

Basic information about this protein and its source genome.

Accession
VK055_1288
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79912.1
Status
annotated
Amino acids
79
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
85.89

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.002
Structure A0A0H3GRQ5
Pocket Pocket 1
P2Rank
Structure A0A0H3GRQ5
Pocket No pockets
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 53 / 4744 genomes with a hit
Normalized 0.011

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 18 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 18 Phobius SIGNAL_PEPTIDE Signal peptide region
14 18 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
28 74 Pfam PF03891 Domain of unknown function (DUF333)
28 74 InterPro IPR005590 Protein of unknown function DUF333
17 78 PANTHER PTHR38008 HEMOLYSIN-RELATED
4 13 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
19 79 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 15 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
1 3 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GRQ5 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GRQ5
AlphaFold — — full sequence — Viewing
ColabFold VK055_1288
ColabFold — — full sequence — Loaded