Protein profile

VK055_1354

protein involved in stress resistance and biofilm formation

Genome: KpATCC43816

Gene: AIK79977.1 ycfR Structure source: AlphaFold + ColabFold UniProt A0A0H3GRJ5
Export view
Amino acids 85
Annotations 0
Features 15
PDB binders 0
Druggability 0.001

Overview

Basic information about this protein and its source genome.

Accession
VK055_1354
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79977.1 ycfR
Status
annotated
Amino acids
85
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
75.32

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.001
Structure A0A0H3GRJ5
Pocket Pocket 2
P2Rank
Structure A0A0H3GRJ5
Pocket No pockets
ColabFold model
FPocket 0.122 · Pocket 3
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 77 / 4744 genomes with a hit
Normalized 0.016

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

15 records
Show feature table
Start End DB Term Name
1 22 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
1 85 PANTHER PTHR34156 OUTER MEMBRANE PROTEIN-RELATED-RELATED
34 85 Pfam PF07338 YdgH/BhsA/McbA-like domain
34 85 InterPro IPR010854 YdgH/BhsA/McbA-like domain
3 85 SUPERFAMILY SSF159871 YdgH-like
3 85 InterPro IPR036275 YdgH-like superfamily
20 85 Gene3D G3DSA:3.30.1660.10 -
20 85 InterPro IPR025543 Dodecin-like
23 85 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
22 85 FunFam G3DSA:3.30.1660.10:FF:000001 Multiple stress resistance protein BhsA
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
19 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
7 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

No pockets are loaded yet for the displayed AlphaFold model AF_A0A0H3GRJ5 structure. Run experimental pocket backfill to show FPocket/P2Rank overlays on this structure.

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GRJ5
AlphaFold — — full sequence — Viewing
ColabFold VK055_1354
ColabFold — — full sequence — Loaded