Metabolic network

VK055_1361

beta-hexosaminidase

Back to protein
Network centrality 0.00156 top 88.6%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Amino sugar and nucleotide sugar metabolism, no isoenzyme backup detected, more central than 88.6% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Amino sugar and nucleotide sugar metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-12625

EC 3.2.1.52 · RXN-12625 · not reversible · no isoenzyme backup

Consuming chokepoint
N,N'-diacetylchitobiose H2O
→
2 N-acetyl-D-glucosamine

RXN-12626

EC 3.2.1.52 · RXN-12626 · not reversible · no isoenzyme backup

Producing chokepoint
N,N',N''-triacetylchitotriose H2O
→
N,N'-diacetylchitobiose N-acetyl-D-glucosamine

RXN-21432

EC 3.2.1.52 · RXN-21432 · not reversible · no isoenzyme backup

N-acetyl-beta-D-glucosaminyl-(1 -> 4)-N-acetyl-D-muramate H2O
→
N-acetyl-D-glucosamine N-acetyl-D-muramate

RXN-21432-CPD-23334/WATER//CPD-12541/NACMUR.34.

EC - · RXN-21432-CPD-23334/WATER//CPD-12541/NACMUR.34. · not reversible · no isoenzyme backup

N-acetyl-beta-D-glucosaminyl-(1 -> 4)-N-acetyl-D-muramate H2O
→
N-acetyl-alpha-D-glucosamine N-acetyl-D-muramate

RXN-22591

EC 3.2.1.52 · RXN-22591 · not reversible · no isoenzyme backup

a peptidoglycan H2O
→
a peptidoglycan with N-acetyl-beta-D-glucosamine at the reducing end a peptidoglycan with N-acetylmuramoyl-pentapeptide at the non-reducing end

RXN-22612

EC 3.2.1.52 · RXN-22612 · not reversible · no isoenzyme backup

a peptidoglycan (L. plantarum) H2O
→
a peptidoglycan with N-acetyl-beta-D-glucosamine at the reducing end (L. plantarum) a peptidoglycan with N-acetylmuramoyl-pentadepsipeptide at the non-reducing end (L. plantarum)

RXN0-5226

EC 3.2.1.52 · RXN0-5226 · not reversible · no isoenzyme backup

N-acetyl-beta-D-glucosamine-1,6-anhydro-N-acetyl-beta-D-muramate H2O
→
N-acetyl-D-glucosamine 1,6-anhydro-N-acetyl-beta-D-muramate

RXN0-5226-CPD0-1081/WATER//CPD-12541/CPD0-882.36.

EC - · RXN0-5226-CPD0-1081/WATER//CPD-12541/CPD0-882.36. · not reversible · no isoenzyme backup

N-acetyl-beta-D-glucosamine-1,6-anhydro-N-acetyl-beta-D-muramate H2O
→
N-acetyl-alpha-D-glucosamine 1,6-anhydro-N-acetyl-beta-D-muramate

3.2.1.52-RXN

EC 3.2.1.52 · 3.2.1.52-RXN · not reversible · no isoenzyme backup

an N-acetyl-beta-D-hexosaminide H2O
→
an N-acetyl-beta-D-hexosamine an alcohol

Imported from KpATCC43816.sbml · 2026-07-09