Protein profile

VK055_1364

hypothetical protein

Genome: KpATCC43816

Gene: AIK79987.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMU1
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Amino acids 119
Annotations 0
Features 11
PDB binders 0
Druggability 0.421

Overview

Basic information about this protein and its source genome.

Accession
VK055_1364
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK79987.1
Status
annotated
Amino acids
119
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
84.69

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.421
Structure A0A0H3GMU1
Pocket Pocket 1
P2Rank
Structure A0A0H3GMU1
Pocket No pockets
ColabFold model
FPocket 0.057 · Pocket 2
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 62 / 4744 genomes with a hit
Normalized 0.013

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
28 118 Pfam PF07233 Protein of unknown function (DUF1425)
28 118 InterPro IPR010824 Protein of unknown function DUF1425
18 118 CDD cd09030 DUF1425
18 118 InterPro IPR010824 Protein of unknown function DUF1425
3 10 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 2 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
16 119 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 15 Phobius SIGNAL_PEPTIDE Signal peptide region
11 15 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
15 118 Gene3D G3DSA:2.60.40.3230 -
15 118 InterPro IPR038483 YcfL-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMU1
AlphaFold — — full sequence — Viewing
ColabFold VK055_1364
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.421
2 0.001
3 0.0