Protein profile

VK055_1419

sel1 repeat family protein

Genome: KpATCC43816

Gene: AIK80040.1 Structure source: ColabFold
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Amino acids 325
Annotations 1
Features 41
PDB binders 0
Druggability 0.571

Overview

Basic information about this protein and its source genome.

Accession
VK055_1419
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80040.1
Status
annotated
Amino acids
325
Structure source
ColabFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
32.593
Human E-value
1.7e-07
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
37.624
Localization
Extracellular
ColabFold pLDDT
95.9

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.571
Structure CB_VK055_1419
Pocket Pocket 4
P2Rank 0.112
Structure CB_VK055_1419
Pocket Pocket 1
ColabFold model
FPocket 0.571 · Pocket 4
P2Rank 0.112 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

41 records
Show feature table
Start End DB Term Name
102 322 SUPERFAMILY SSF81901 HCP-like
1 104 SUPERFAMILY SSF81901 HCP-like
245 279 Pfam PF08238 Sel1 repeat
245 279 InterPro IPR006597 Sel1-like repeat
136 170 Pfam PF08238 Sel1 repeat
136 170 InterPro IPR006597 Sel1-like repeat
1 27 Pfam PF08238 Sel1 repeat
1 27 InterPro IPR006597 Sel1-like repeat
65 99 Pfam PF08238 Sel1 repeat
65 99 InterPro IPR006597 Sel1-like repeat
28 59 Pfam PF08238 Sel1 repeat
28 59 InterPro IPR006597 Sel1-like repeat
210 243 Pfam PF08238 Sel1 repeat
210 243 InterPro IPR006597 Sel1-like repeat
280 315 Pfam PF08238 Sel1 repeat
280 315 InterPro IPR006597 Sel1-like repeat
102 135 Pfam PF08238 Sel1 repeat
102 135 InterPro IPR006597 Sel1-like repeat
173 206 Pfam PF08238 Sel1 repeat
173 206 InterPro IPR006597 Sel1-like repeat
1 95 PANTHER PTHR11102 SEL-1-LIKE PROTEIN
136 171 SMART SM00671 sel1
136 171 InterPro IPR006597 Sel1-like repeat
208 243 SMART SM00671 sel1
208 243 InterPro IPR006597 Sel1-like repeat
28 63 SMART SM00671 sel1
28 63 InterPro IPR006597 Sel1-like repeat
244 279 SMART SM00671 sel1
244 279 InterPro IPR006597 Sel1-like repeat
1 27 SMART SM00671 sel1
64 99 SMART SM00671 sel1
64 99 InterPro IPR006597 Sel1-like repeat
280 315 SMART SM00671 sel1
172 207 SMART SM00671 sel1
172 207 InterPro IPR006597 Sel1-like repeat
100 135 SMART SM00671 sel1
100 135 InterPro IPR006597 Sel1-like repeat
190 324 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
190 324 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
1 172 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
1 172 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_1419
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.571
1 0.002
2 0.0
5 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.69 0.112
2 3.04 0.081
3 2.95 0.076
4 2.29 0.047