Protein profile

VK055_1425

phage integrase

Genome: KpATCC43816

Gene: AIK80046.1 Structure source: ColabFold
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Amino acids 223
Annotations 1
Features 11
PDB binders 0
Druggability 0.497

Overview

Basic information about this protein and its source genome.

Accession
VK055_1425
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80046.1
Status
annotated
Amino acids
223
Structure source
ColabFold
GO
GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
87.5

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.497
Structure CB_VK055_1425
Pocket Pocket 1
P2Rank
Structure CB_VK055_1425
Pocket No pockets
ColabFold model
FPocket 0.497 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 8 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

Sequence Features

Domain/signature hits from InterPro and related databases.

11 records
Show feature table
Start End DB Term Name
15 223 PANTHER PTHR30629 PROPHAGE INTEGRASE
15 54 Pfam PF13356 Arm DNA-binding domain
15 54 InterPro IPR025166 Integrase, DNA-binding domain
67 148 ProSiteProfiles PS51900 Core-binding (CB) domain profile.
67 148 InterPro IPR044068 Core-binding (CB) domain
68 222 SUPERFAMILY SSF56349 DNA breaking-rejoining enzymes
68 222 InterPro IPR011010 DNA breaking-rejoining enzyme, catalytic core
71 150 Gene3D G3DSA:1.10.150.130 -
71 150 InterPro IPR010998 Integrase/recombinase, N-terminal
3 70 Gene3D G3DSA:3.30.160.390 -
3 70 InterPro IPR038488 Integrase, DNA-binding domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_1425
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.497
5 0.02
10 0.002
6 0.0