Metabolic network

VK055_1796

oxoglutarate dehydrogenase (succinyl-transferring), E1 component

Back to protein
Network centrality 0.00512 top 89.6%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing & consuming chokepoint reaction, no isoenzyme backup detected, more central than 89.6% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

No specific KEGG pathway assigned - this reaction either has no KEGG mapping, or only matches a generic overview map with no route-level information.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

2OXOGLUTDECARB-RXN

EC 1.2.4.2 · 2OXOGLUTDECARB-RXN · not reversible · no isoenzyme backup

Producing & consuming chokepoint
2-oxoglutarate a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine H+
→
a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine CO2

Imported from KpATCC43816.sbml · 2026-07-09