Metabolic network

VK055_1845

tRNA-i(6)A37 thiotransferase enzyme MiaB

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Network centrality 0
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction.

Pathways

KEGG pathways this gene's reaction(s) belong to.

No specific KEGG pathway assigned - this reaction either has no KEGG mapping, or only matches a generic overview map with no route-level information.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN0-5063

EC 2.8.4.3 · RXN0-5063 · not reversible · 2 isoenzymes

Consuming chokepoint
2 S-adenosyl-L-methionine N6-(3-methylbut-2-en-1-yl)-adenine37 in tRNA a [3Fe-4S] iron-sulfur cluster a reduced two electron carrier
→
2-(methylsulfanyl)-N6-prenyladenosine37 in tRNA S-adenosyl-L-homocysteine a [3Fe-3S] iron-sulfur cluster 5'-deoxyadenosine L-methionine an oxidized electron carrier 2 H+

Imported from KpATCC43816.sbml · 2026-07-09