Metabolic network

VK055_1858

leucine--tRNA ligase

Back to protein
Network centrality 0.01027 top 91.1%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction in Aminoacyl-tRNA biosynthesis, no isoenzyme backup detected, more central than 91.1% of genes in this genome.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Aminoacyl-tRNA biosynthesis

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

Select a node
EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-23890

EC - · RXN-23890 · not reversible · no isoenzyme backup

L-leucine ATP H+
→
(L-leucyl)adenylate diphosphate

RXN-23949

EC - · RXN-23949 · not reversible · no isoenzyme backup

Producing chokepoint
L-norvaline ATP H+
→
(L-norvalyl)adenylate diphosphate

Imported from KpATCC43816.sbml · 2026-07-09