Protein profile

VK055_1937

hypothetical protein

Genome: KpATCC43816

Gene: AIK80543.1 Structure source: AlphaFold + ColabFold UniProt A0A483NYA1
Export view
Amino acids 203
Annotations 0
Features 16
PDB binders 0
Druggability 0.355

Overview

Basic information about this protein and its source genome.

Accession
VK055_1937
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK80543.1
Status
annotated
Amino acids
203
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
86.96

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.355
Structure A0A483NYA1
Pocket Pocket 2
P2Rank
Structure A0A483NYA1
Pocket No pockets
ColabFold model
FPocket 0.432 · Pocket 6
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 15 / 4744 genomes with a hit
Normalized 0.003

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

16 records
Show feature table
Start End DB Term Name
1 27 SignalP_EUK SignalP-noTM SignalP-noTM
28 203 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 22 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
1 27 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
1 27 Phobius SIGNAL_PEPTIDE Signal peptide region
1 7 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
8 19 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
15 191 Pfam PF10054 Predicted periplasmic lipoprotein (DUF2291)
15 191 InterPro IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein
20 27 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
7 25 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
2 201 PIRSF PIRSF033535 UCP033535_plp
2 201 InterPro IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein
49 199 SUPERFAMILY SSF141318 TM0957-like
49 199 InterPro IPR036215 TM0957-like superfamily
1 21 SignalP_GRAM_NEGATIVE SignalP-noTM SignalP-noTM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

Legend High Medium Low

Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483NYA1
AlphaFold — — full sequence — Viewing
ColabFold VK055_1937
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.355
1 0.147
6 0.074
9 0.01