Metabolic network

VK055_2071

tRNA 2-selenouridine synthase

Back to protein
Network centrality 0.01017 top 90.5%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing chokepoint reaction, no isoenzyme backup detected, more central than 90.5% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

No specific KEGG pathway assigned - this reaction either has no KEGG mapping, or only matches a generic overview map with no route-level information.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-20762

EC 2.9.1.3 · RXN-20762 · not reversible · no isoenzyme backup

selenophosphate a 5-carboxymethylaminomethyl-2-thiouridine34 in tRNA geranyl diphosphate H2O
→
a 5-carboxymethylaminomethyl-2-selenouridine34 in tRNA (2E)-3,7-dimethylocta-2,6-diene-1-thiol diphosphate phosphate

RXN-24092

EC - · RXN-24092 · not reversible · no isoenzyme backup

a 5-carboxymethylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA H2O
→
a 5-carboxymethylaminomethyl-2-selenouridine34 in tRNA phosphate

RXN-24091

EC - · RXN-24091 · not reversible · no isoenzyme backup

selenophosphate a 5-carboxymethylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA
→
a 5-carboxymethylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA (2E)-3,7-dimethylocta-2,6-diene-1-thiol

RXN-24090

EC - · RXN-24090 · not reversible · no isoenzyme backup

geranyl diphosphate a 5-carboxymethylaminomethyl-2-thiouridine34 in tRNA
→
a 5-carboxymethylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA diphosphate

RXN0-2281

EC 2.9.1.3 · RXN0-2281 · not reversible · no isoenzyme backup

selenophosphate a 5-[(methylamino)methyl]-2-thiouridine34 in tRNA geranyl diphosphate H2O
→
a 5-methylaminomethyl-2-selenouridine34 in tRNA (2E)-3,7-dimethylocta-2,6-diene-1-thiol diphosphate phosphate

RXN-20755

EC - · RXN-20755 · not reversible · no isoenzyme backup

Producing chokepoint
geranyl diphosphate a 5-[(methylamino)methyl]-2-thiouridine34 in tRNA
→
a 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA diphosphate

RXN-20757

EC - · RXN-20757 · not reversible · no isoenzyme backup

Consuming chokepoint
a 5-methylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA H2O
→
a 5-methylaminomethyl-2-selenouridine34 in tRNA phosphate

RXN-20756

EC - · RXN-20756 · not reversible · no isoenzyme backup

Producing & consuming chokepoint
selenophosphate a 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA
→
a 5-methylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA (2E)-3,7-dimethylocta-2,6-diene-1-thiol

Imported from KpATCC43816.sbml · 2026-07-09