Protein profile

VK055_2403

lipo, PulS/OutS family protein

Genome: KpATCC43816

Gene: AIK81000.1 Structure source: AlphaFold + ColabFold UniProt A0A235KB21
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Amino acids 114
Annotations 1
Features 6
PDB binders 0
Druggability 0.497

Overview

Basic information about this protein and its source genome.

Accession
VK055_2403
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK81000.1
Status
annotated
Amino acids
114
Structure source
AlphaFold + ColabFold
GO
GO:0006886 The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
OuterMembrane
ColabFold pLDDT
89.22

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.497
Structure A0A235KB21
Pocket Pocket 3
P2Rank 0.077
Structure A0A235KB21
Pocket Pocket 1
ColabFold model
FPocket 0.265 · Pocket 1
P2Rank 0.068 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 7 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0006886 The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
2 110 NCBIfam TIGR01004 type II secretion system pilot lipoprotein GspS
2 110 InterPro IPR005699 Chaperone lipoprotein, PulS/OutS
5 108 Pfam PF09691 Type II secretion system pilotin lipoprotein (PulS_OutS)
5 108 InterPro IPR019114 Chaperone lipoprotein, PulS/OutS-like
20 112 Gene3D G3DSA:1.20.58.1630 Chaperone lipoprotein PulS/OutS
20 112 InterPro IPR038432 PulS/OutS-like superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A235KB21
AlphaFold — — full sequence — Viewing
ColabFold VK055_2403
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.497
1 0.209
2 0.15

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 2.96 0.077
2 1.44 0.016