Protein profile

VK055_2447

hypothetical protein

Genome: KpATCC43816

Gene: AIK81044.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GMN9
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Amino acids 482
Annotations 0
Features 7
PDB binders 0
Druggability 0.579

Overview

Basic information about this protein and its source genome.

Accession
VK055_2447
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK81044.1
Status
annotated
Amino acids
482
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
69.35

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.579
Structure A0A0H3GMN9
Pocket Pocket 24
P2Rank 0.369
Structure A0A0H3GMN9
Pocket Pocket 1
ColabFold model
FPocket 0.027 · Pocket 32
P2Rank 0.337 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 51 / 4744 genomes with a hit
Normalized 0.011

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
2 476 PANTHER PTHR40269 OUTER MEMBRANE PROTEIN-RELATED
2 476 InterPro IPR021728 Protein of unknown function DUF3300
318 461 MobiDBLite mobidb-lite consensus disorder prediction
6 275 Pfam PF11737 Protein of unknown function (DUF3300)
6 275 InterPro IPR021728 Protein of unknown function DUF3300
463 482 MobiDBLite mobidb-lite consensus disorder prediction
295 482 MobiDBLite mobidb-lite consensus disorder prediction

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GMN9
AlphaFold — — full sequence — Viewing
ColabFold VK055_2447
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
33 0.037
40 0.016
39 0.006
35 0.002

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.18 0.369
2 3.47 0.101
3 3.42 0.098
4 2.06 0.038
5 1.38 0.014