QUINATE-5-DEHYDROGENASE-RXN-QUINATE/NADP//DEHYDROQUINATE/NADPH/PROTON.42.
EC - · QUINATE-5-DEHYDROGENASE-RXN-QUINATE/NADP//DEHYDROQUINATE/NADPH/PROTON.42. · not reversible · no isoenzyme backup
Network centrality
0.24823
top 99.1%
Chokepoint
Yes
Attractive metabolic target: catalyzes a producing chokepoint reaction in Phenylalanine, tyrosine and tryptophan biosynthesis, more central than 99.1% of genes in this genome, no human homolog detected.
Pathways
KEGG pathways this gene's reaction(s) belong to.
Network
Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.
Reaction catalyzed by this protein
Chokepoint reaction
Neighbor reaction
Pathway grouping (2+ reactions sharing a route)
Connected reaction (arrow shows direction, when known)
⇌ Reversible reaction (double arrow)
Cross-pathway connection
Selected reaction
Click a node in the network above, or a row in the table below, to inspect it here.
Select a node
- EC
- -
- Pathway
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- Genes
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- Role
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- Isoenzymes
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Catalyzed reactions
Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.
RXN-11174-SHIKIMATE/NAD//3-DEHYDRO-SHIKIMATE/NADH/PROTON.47.
EC - · RXN-11174-SHIKIMATE/NAD//3-DEHYDRO-SHIKIMATE/NADH/PROTON.47. · not reversible · no isoenzyme backup
shikimate
NAD+
→
3-dehydroshikimate
NADH
H+
QUINATE-5-DEHYDROGENASE-RXN-QUINATE/NAD//DEHYDROQUINATE/NADH/PROTON.40.
EC - · QUINATE-5-DEHYDROGENASE-RXN-QUINATE/NAD//DEHYDROQUINATE/NADH/PROTON.40. · not reversible · no isoenzyme backup
L-quinate
NAD+
→
3-dehydroquinate
NADH
H+
SHIKIMATE-5-DEHYDROGENASE-RXN
EC 1.1.1.25 · SHIKIMATE-5-DEHYDROGENASE-RXN · not reversible · 2 isoenzymes
H+
3-dehydroshikimate
NADPH
→
shikimate
NADP+
Imported from KpATCC43816.sbml · 2026-07-09