Protein profile

VK055_2764

hypothetical protein

Genome: KpATCC43816

Gene: AIK81354.1 Structure source: AlphaFold + ColabFold UniProt A0A422ZFX8
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Amino acids 283
Annotations 0
Features 2
PDB binders 0
Druggability 0.574

Overview

Basic information about this protein and its source genome.

Accession
VK055_2764
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK81354.1
Status
annotated
Amino acids
283
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
87.9

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.574
Structure A0A422ZFX8
Pocket Pocket 21
P2Rank 0.387
Structure A0A422ZFX8
Pocket Pocket 1
ColabFold model
FPocket 0.211 · Pocket 20
P2Rank 0.621 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 11 / 4744 genomes with a hit
Normalized 0.002

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

2 records
Show feature table
Start End DB Term Name
4 258 Pfam PF19924 Family of unknown function (DUF6387)
4 258 InterPro IPR045664 Protein of unknown function DUF6387

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A422ZFX8
AlphaFold — — full sequence — Viewing
ColabFold VK055_2764
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
21 0.574
20 0.036
18 0.003
4 0.001

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.52 0.387
2 7.0 0.303
3 3.64 0.11
4 2.48 0.056
5 1.4 0.015