Protein profile

VK055_3535

mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein

Genome: KpATCC43816

Gene: AIK82091.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H010
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Amino acids 187
Annotations 1
Features 6
PDB binders 0
Druggability 0.837

Overview

Basic information about this protein and its source genome.

Accession
VK055_3535
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82091.1
Status
annotated
Amino acids
187
Structure source
AlphaFold + ColabFold
GO
GO:0004040 Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH4+.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
31.25
Localization
Unknown
ColabFold pLDDT
92.47

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.837
Structure A0A0H3H010
Pocket Pocket 2
P2Rank 0.537
Structure A0A0H3H010
Pocket Pocket 1
ColabFold model
FPocket 0.56 · Pocket 2
P2Rank 0.483 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 66 / 4744 genomes with a hit
Normalized 0.014

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0004040 Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH4+.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
1 185 PANTHER PTHR40572 PROTEIN BAX
43 169 SMART SM00047 Lysozyme_4
43 169 InterPro IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain
57 180 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
57 180 InterPro IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain
50 181 Gene3D G3DSA:1.10.530.10 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H010
AlphaFold — — full sequence — Viewing
ColabFold VK055_3535
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.837

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 10.39 0.558
2 1.48 0.02
3 1.47 0.02