Protein profile

VK055_3688

phosphoribosyl transferase domain protein

Genome: KpATCC43816

Gene: AIK82243.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GWT4
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Amino acids 212
Annotations 0
Features 8
PDB binders 0
Druggability 0.673

Overview

Basic information about this protein and its source genome.

Accession
VK055_3688
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82243.1
Status
annotated
Amino acids
212
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
87.13

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.673
Structure A0A0H3GWT4
Pocket Pocket 13
P2Rank 0.388
Structure A0A0H3GWT4
Pocket Pocket 1
ColabFold model
FPocket 0.176 · Pocket 20
P2Rank 0.441 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 88 / 4744 genomes with a hit
Normalized 0.019

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

8 records
Show feature table
Start End DB Term Name
81 211 Gene3D G3DSA:3.40.50.2020 -
81 211 InterPro IPR029057 Phosphoribosyltransferase-like
98 208 CDD cd06223 PRTases_typeI
98 208 InterPro IPR000836 Phosphoribosyltransferase domain
5 211 PANTHER PTHR47505 DNA UTILIZATION PROTEIN YHGH
1 34 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
34 210 SUPERFAMILY SSF53271 PRTase-like
34 210 InterPro IPR029057 Phosphoribosyltransferase-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GWT4
AlphaFold — — full sequence — Viewing
ColabFold VK055_3688
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
13 0.673
9 0.197
3 0.135
1 0.004

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 8.54 0.388
2 4.43 0.154
3 2.58 0.06
4 2.51 0.057