Protein profile

VK055_3743

sensory box protein

Genome: KpATCC43816

Gene: AIK82298.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3H3Y0
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Amino acids 240
Annotations 0
Features 6
PDB binders 0
Druggability 0.456

Overview

Basic information about this protein and its source genome.

Accession
VK055_3743
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82298.1
Status
annotated
Amino acids
240
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
68.037
DEG E-value
2.09e-102
Localization
Cytoplasmic
ColabFold pLDDT
84.98

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.456
Structure A0A0H3H3Y0
Pocket Pocket 4
P2Rank 0.566
Structure A0A0H3H3Y0
Pocket Pocket 1
ColabFold model
FPocket 0.363 · Pocket 1
P2Rank 0.631 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 146 / 4744 genomes with a hit
Normalized 0.031

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

6 records
Show feature table
Start End DB Term Name
17 234 PANTHER PTHR35568 TRANSCRIPTIONAL REGULATOR DAUR
17 234 InterPro IPR039446 Transcriptional regulator DauR-like
171 228 Pfam PF13309 HTH domain
171 228 InterPro IPR039445 Transcriptional regulator DauR-like, HTH domain
29 136 Pfam PF08348 YheO-like PAS domain
29 136 InterPro IPR013559 YheO-like

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3H3Y0
AlphaFold — — full sequence — Viewing
ColabFold VK055_3743
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.346
8 0.04
1 0.006
16 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 12.44 0.566
2 0.84 0.003