Protein profile

VK055_3831

hypothetical protein

Genome: KpATCC43816

Gene: AIK82381.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GTV4
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Amino acids 87
Annotations 0
Features 17
PDB binders 0
Druggability 0.443

Overview

Basic information about this protein and its source genome.

Accession
VK055_3831
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82381.1
Status
annotated
Amino acids
87
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
81.89

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.443
Structure A0A0H3GTV4
Pocket Pocket 2
P2Rank
Structure A0A0H3GTV4
Pocket No pockets
ColabFold model
FPocket 0.147 · Pocket 6
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 69 / 4744 genomes with a hit
Normalized 0.015

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

17 records
Show feature table
Start End DB Term Name
1 87 NCBIfam NF033776 peroxide/acid stress response protein YhcN
1 87 InterPro IPR047775 Peroxide/acid stress response protein YhcN-like
7 26 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane.
1 22 SignalP_EUK SignalP-noTM SignalP-noTM
22 87 Gene3D G3DSA:3.30.1660.10 -
22 87 InterPro IPR025543 Dodecin-like
1 22 Phobius SIGNAL_PEPTIDE Signal peptide region
3 87 SUPERFAMILY SSF159871 YdgH-like
3 87 InterPro IPR036275 YdgH-like superfamily
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
19 22 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
35 87 Pfam PF07338 YdgH/BhsA/McbA-like domain
35 87 InterPro IPR010854 YdgH/BhsA/McbA-like domain
7 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 22 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM
23 87 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
1 87 PANTHER PTHR34156 OUTER MEMBRANE PROTEIN-RELATED-RELATED

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GTV4
AlphaFold — — full sequence — Viewing
ColabFold VK055_3831
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
4 0.019
1 0.006
3 0.005
5 0.0