Protein profile

VK055_3887

CRS1 / YhbY domain protein

Genome: KpATCC43816

Gene: AIK82437.1 Structure source: AlphaFold + ColabFold UniProt A0A080SZF0
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Amino acids 97
Annotations 1
Features 13
PDB binders 0
Druggability 0.471

Overview

Basic information about this protein and its source genome.

Accession
VK055_3887
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82437.1
Status
annotated
Amino acids
97
Structure source
AlphaFold + ColabFold
GO
GO:0003723 Binding to an RNA molecule or a portion thereof.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
48.315
DEG E-value
7.15e-22
Localization
Cytoplasmic
ColabFold pLDDT
92.95

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.471
Structure A0A080SZF0
Pocket Pocket 1
P2Rank
Structure A0A080SZF0
Pocket No pockets
ColabFold model
FPocket 0.687 · Pocket 1
Core conservation Conserved core gene
Roary core
CoreCruncher core
Gut microbiome 155 / 4744 genomes with a hit
Normalized 0.033

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0003723 Binding to an RNA molecule or a portion thereof.

Sequence Features

Domain/signature hits from InterPro and related databases.

13 records
Show feature table
Start End DB Term Name
1 97 PANTHER PTHR40065 RNA-BINDING PROTEIN YHBY
1 95 SUPERFAMILY SSF75471 YhbY-like
1 95 InterPro IPR035920 YhbY-like superfamily
3 97 NCBIfam TIGR00253 ribosome assembly RNA-binding protein YhbY
3 97 InterPro IPR017924 RNA-binding protein YhbY
1 97 FunFam G3DSA:3.30.110.60:FF:000001 RNA-binding protein YhbY
1 97 ProSiteProfiles PS51295 CRM domain profile.
1 97 InterPro IPR001890 RNA-binding, CRM domain
3 86 SMART SM01103 CRS1_YhbY_2
3 86 InterPro IPR001890 RNA-binding, CRM domain
1 97 Gene3D G3DSA:3.30.110.60 -
1 97 InterPro IPR035920 YhbY-like superfamily
3 86 Pfam PF01985 CRS1 / YhbY (CRM) domain

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A080SZF0
AlphaFold — — full sequence — Viewing
ColabFold VK055_3887
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
1 0.471
3 0.006
4 0.001
2 0.0