Protein profile

VK055_3918

putative uPF0306 protein yhbP

Genome: KpATCC43816

Gene: AIK82465.1 Structure source: AlphaFold + ColabFold UniProt A0A0H3GXZ9
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Amino acids 147
Annotations 0
Features 7
PDB binders 0
Druggability 0.426

Overview

Basic information about this protein and its source genome.

Accession
VK055_3918
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82465.1
Status
annotated
Amino acids
147
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
Y
DEG identity (%)
75.51
DEG E-value
3.7e-82
Localization
Unknown
ColabFold pLDDT
94.33

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.426
Structure A0A0H3GXZ9
Pocket Pocket 3
P2Rank 0.019
Structure A0A0H3GXZ9
Pocket Pocket 1
ColabFold model
FPocket 0.454 · Pocket 5
P2Rank 0.02 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 88 / 4744 genomes with a hit
Normalized 0.019

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
3 140 Hamap MF_00764 UPF0306 protein YhbP [yhbP].
3 140 InterPro IPR011194 Uncharacterised protein family UPF0306
2 139 Gene3D G3DSA:2.30.110.10 -
2 139 InterPro IPR012349 FMN-binding split barrel
1 145 PIRSF PIRSF009554 UCP009554
1 145 InterPro IPR011194 Uncharacterised protein family UPF0306
3 140 SUPERFAMILY SSF50475 FMN-binding split barrel

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A0H3GXZ9
AlphaFold — — full sequence — Viewing
ColabFold VK055_3918
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
3 0.426
6 0.178
8 0.041
2 0.002

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.54 0.019