Protein profile

VK055_3931

hypothetical protein

Genome: KpATCC43816

Gene: AIK82479.1 Structure source: Experimental + ColabFold UniProt A6TEE6
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Amino acids 154
Annotations 0
Features 12
PDB binders 0
Druggability 0.271

Overview

Basic information about this protein and its source genome.

Accession
VK055_3931
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82479.1
Status
annotated
Amino acids
154
Structure source
Experimental + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
CytoplasmicMembrane
ColabFold pLDDT
86.33

Selected Druggability evidence

PDB experimental structure

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.271
Structure 3F1Z
Pocket Pocket 2
P2Rank
Structure 3F1Z
Pocket No pockets
ColabFold model
FPocket 0.099 · Pocket 1
P2Rank 0.021 · Pocket 1
Core conservation Accessory gene
Roary core
CoreCruncher accessory
Gut microbiome 4 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

12 records
Show feature table
Start End DB Term Name
1 23 SignalP_EUK SignalP-noTM SignalP-noTM
1 23 Phobius SIGNAL_PEPTIDE Signal peptide region
1 6 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
39 154 Gene3D G3DSA:2.40.50.140 -
39 154 InterPro IPR012340 Nucleic acid-binding, OB-fold
1 20 ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile.
7 18 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
1 151 Pfam PF12869 tRNA_anti-like
1 151 InterPro IPR024422 Protein of unknown function, OB-fold-containing
24 154 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
19 23 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
1 25 SignalP_GRAM_POSITIVE SignalP-TM SignalP-TM

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

1 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
PDB 3F1Z
X-ray 20.00 Å - —
PDBe RCSB PDBj File
Viewing
ColabFold VK055_3931
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.792
1 0.55
31 0.258

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 17.74 0.807
2 16.28 0.775
3 15.57 0.756
4 15.53 0.755
5 14.15 0.713