Protein profile

VK055_4071

gram-negative pili assembly chaperone, C-terminal domain protein

Genome: KpATCC43816

Gene: AIK82618.1 Structure source: ColabFold
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Amino acids 103
Annotations 0
Features 7
PDB binders 0
Druggability 0.289

Overview

Basic information about this protein and its source genome.

Accession
VK055_4071
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82618.1
Status
annotated
Amino acids
103
Structure source
ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
38.71
Localization
Periplasmic
ColabFold pLDDT
86.5

Selected Druggability evidence

ColabFold / curated model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.289
Structure CB_VK055_4071
Pocket Pocket 6
P2Rank 0.013
Structure CB_VK055_4071
Pocket Pocket 1
ColabFold model
FPocket 0.289 · Pocket 6
P2Rank 0.013 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 3 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

7 records
Show feature table
Start End DB Term Name
14 95 Gene3D G3DSA:2.60.40.10 Immunoglobulins
14 95 InterPro IPR013783 Immunoglobulin-like fold
33 92 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain
33 92 InterPro IPR016148 Pili assembly chaperone, C-terminal
2 99 PANTHER PTHR30251 PILUS ASSEMBLY CHAPERONE
17 92 SUPERFAMILY SSF49584 Periplasmic chaperone C-domain
17 92 InterPro IPR036316 Pili assembly chaperone, C-terminal domain superfamily

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 1

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
ColabFold VK055_4071
ColabFold — — full sequence — Viewing
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
6 0.289
1 0.07
5 0.007
3 0.001

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 1.34 0.013