Protein profile

VK055_4182

sel1 repeat family protein

Genome: KpATCC43816

Gene: AIK82727.1 Structure source: AlphaFold + ColabFold UniProt A0A483TV37
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Amino acids 440
Annotations 1
Features 34
PDB binders 0
Druggability 0.287

Overview

Basic information about this protein and its source genome.

Accession
VK055_4182
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK82727.1
Status
annotated
Amino acids
440
Structure source
AlphaFold + ColabFold
GO
GO:0005515 Binding to a protein.

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
35.556
Human E-value
1.3e-13
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
40.566
Localization
Extracellular
ColabFold pLDDT
63.56

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.287
Structure A0A483TV37
Pocket Pocket 20
P2Rank 0.422
Structure A0A483TV37
Pocket Pocket 1
ColabFold model
FPocket 0.049 · Pocket 27
P2Rank 0.123 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1

Sequence Features

Domain/signature hits from InterPro and related databases.

34 records
Show feature table
Start End DB Term Name
168 259 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
168 259 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
38 167 Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
38 167 InterPro IPR011990 Tetratricopeptide-like helical domain superfamily
36 40 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide.
204 238 Pfam PF08238 Sel1 repeat
204 238 InterPro IPR006597 Sel1-like repeat
59 93 Pfam PF08238 Sel1 repeat
59 93 InterPro IPR006597 Sel1-like repeat
133 165 Pfam PF08238 Sel1 repeat
133 165 InterPro IPR006597 Sel1-like repeat
173 202 Pfam PF08238 Sel1 repeat
173 202 InterPro IPR006597 Sel1-like repeat
95 130 Pfam PF08238 Sel1 repeat
95 130 InterPro IPR006597 Sel1-like repeat
1 40 Phobius SIGNAL_PEPTIDE Signal peptide region
38 253 PANTHER PTHR11102 SEL-1-LIKE PROTEIN
24 35 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide.
321 440 MobiDBLite mobidb-lite consensus disorder prediction
41 440 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region.
52 248 SUPERFAMILY SSF81901 HCP-like
358 383 MobiDBLite mobidb-lite consensus disorder prediction
1 23 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide.
398 423 MobiDBLite mobidb-lite consensus disorder prediction
95 130 SMART SM00671 sel1
203 238 SMART SM00671 sel1
203 238 InterPro IPR006597 Sel1-like repeat
167 202 SMART SM00671 sel1
167 202 InterPro IPR006597 Sel1-like repeat
131 166 SMART SM00671 sel1
131 166 InterPro IPR006597 Sel1-like repeat
59 94 SMART SM00671 sel1
59 94 InterPro IPR006597 Sel1-like repeat
342 362 Coils Coil Coil

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A483TV37
AlphaFold — — full sequence — Viewing
ColabFold VK055_4182
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
20 0.287
2 0.048
21 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 9.2 0.422
2 7.21 0.315
3 4.08 0.134