Metabolic network

VK055_4287

phosphoenolpyruvate-protein phosphotransferase

Network centrality 0.0074 top 90.2%
Chokepoint Yes

Attractive metabolic target: catalyzes a producing & consuming chokepoint reaction, no isoenzyme backup detected, more central than 90.2% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

No specific KEGG pathway assigned - this reaction either has no KEGG mapping, or only matches a generic overview map with no route-level information.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

2.7.3.9-RXN

EC 2.7.3.9 · 2.7.3.9-RXN · not reversible · no isoenzyme backup

phosphoenolpyruvate an [HPr]-L-histidine
pyruvate an [HPr protein]-Npi-phospho-L-histidine

RXN-17355

EC - · RXN-17355 · not reversible · no isoenzyme backup

a [PTS enzyme I]-Npi-phospho-L-histidine an [HPr]-L-histidine
a [PTS enzyme I]-L-histidine an [HPr protein]-Npi-phospho-L-histidine

RXN-17354

EC - · RXN-17354 · not reversible · no isoenzyme backup

Producing & consuming chokepoint
phosphoenolpyruvate a [PTS enzyme I]-L-histidine
pyruvate a [PTS enzyme I]-Npi-phospho-L-histidine

Imported from KpATCC43816.sbml · 2026-07-09