Protein profile

VK055_5019

glycosyl transferases group 1 family protein

Genome: KpATCC43816

Gene: AIK83545.1 Structure source: AlphaFold + ColabFold UniProt Q48454
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Amino acids 373
Annotations 1
Features 9
PDB binders 0
Druggability 0.152

Overview

Basic information about this protein and its source genome.

Accession
VK055_5019
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83545.1
Status
annotated
Amino acids
373
Structure source
AlphaFold + ColabFold
GO
GO:0016757 Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).

Target profile

Computed evidence for target prioritization.

Human off-target
hit
Human identity (%)
37.313
Human E-value
6.01e-07
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
28.966
Localization
Cytoplasmic
ColabFold pLDDT
89.2

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.152
Structure Q48454
Pocket Pocket 13
P2Rank 0.956
Structure Q48454
Pocket Pocket 1
ColabFold model
FPocket 0.668 · Pocket 15
P2Rank 0.928 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016757 Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
2 325 PANTHER PTHR45947 SULFOQUINOVOSYL TRANSFERASE SQD2
15 207 Pfam PF13439 Glycosyltransferase Family 4
15 207 InterPro IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain
1 372 SUPERFAMILY SSF53756 UDP-Glycosyltransferase/glycogen phosphorylase
2 373 CDD cd03823 GT4_ExpE7-like
1 216 Gene3D G3DSA:3.40.50.2000 Glycogen Phosphorylase B;
217 340 Gene3D G3DSA:3.40.50.2000 Glycogen Phosphorylase B;
219 325 Pfam PF00534 Glycosyl transferases group 1
219 325 InterPro IPR001296 Glycosyl transferase, family 1

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_Q48454
AlphaFold — — full sequence — Viewing
ColabFold VK055_5019
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 26.6 0.915
2 2.45 0.067