Protein profile

VK055_5020

glycosyl transferases group 1 family protein

Genome: KpATCC43816

Gene: AIK83546.1 Structure source: AlphaFold + ColabFold UniProt A0A4S6NIK9
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Amino acids 388
Annotations 1
Features 4
PDB binders 0
Druggability 0.368

Overview

Basic information about this protein and its source genome.

Accession
VK055_5020
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83546.1
Status
annotated
Amino acids
388
Structure source
AlphaFold + ColabFold
GO
GO:0016740 Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
No hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Cytoplasmic
ColabFold pLDDT
93.27

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.368
Structure A0A4S6NIK9
Pocket Pocket 25
P2Rank 0.528
Structure A0A4S6NIK9
Pocket Pocket 1
ColabFold model
FPocket 0.371 · Pocket 3
P2Rank 0.877 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 0 / 4744 genomes with a hit
Normalized 0

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

1 GO

Gene Ontology (GO)

1
  • GO:0016740 Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

Sequence Features

Domain/signature hits from InterPro and related databases.

4 records
Show feature table
Start End DB Term Name
189 375 Gene3D G3DSA:3.40.50.2000 Glycogen Phosphorylase B;
30 382 Gene3D G3DSA:3.40.50.2000 Glycogen Phosphorylase B;
212 353 Pfam PF13692 Glycosyl transferases group 1
3 382 SUPERFAMILY SSF53756 UDP-Glycosyltransferase/glycogen phosphorylase

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A4S6NIK9
AlphaFold — — full sequence — Viewing
ColabFold VK055_5020
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
2 0.198
16 0.027
12 0.005
26 0.0

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 11.45 0.528
2 3.68 0.112
3 1.75 0.026
4 1.72 0.025
5 0.92 0.004