Metabolic network

VK055_5027

mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Back to protein
Network centrality 0
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction in Amino sugar and nucleotide sugar metabolism, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

Amino sugar and nucleotide sugar metabolism Fructose and mannose metabolism

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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EC
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Pathway
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Genes
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

MANNPISOM-RXN

EC 5.3.1.8 · MANNPISOM-RXN · not reversible · 2 isoenzymes

Consuming chokepoint
D-mannopyranose 6-phosphate
→
beta-D-fructofuranose 6-phosphate

Imported from KpATCC43816.sbml · 2026-07-09