Metabolic network

VK055_5056

cobalamin 5'-phosphate synthase

Network centrality 0.02907 top 93.7%
Chokepoint Yes

Attractive metabolic target: catalyzes a consuming chokepoint reaction, no isoenzyme backup detected, more central than 93.7% of genes in this genome, no human homolog detected.

Pathways

KEGG pathways this gene's reaction(s) belong to.

No specific KEGG pathway assigned - this reaction either has no KEGG mapping, or only matches a generic overview map with no route-level information.

Network

Two-hop reaction neighborhood around this protein; pathway boxes use one primary KEGG route per reaction when several mappings exist. Click a pathway box to open its full route map.

Reaction catalyzed by this protein Chokepoint reaction Neighbor reaction Pathway grouping (2+ reactions sharing a route) Connected reaction (arrow shows direction, when known) ⇌ Reversible reaction (double arrow) Cross-pathway connection

Selected reaction

Click a node in the network above, or a row in the table below, to inspect it here.

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Pathway
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Role
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Isoenzymes
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Catalyzed reactions

Every reaction this gene catalyzes, with substrates/products and isoenzyme backup.

RXN-19318

EC 2.7.8.26 · RXN-19318 · not reversible · no isoenzyme backup

adenosylcobinamide-GDP 2-methyladenine ribotide phosphate
Coalpha-[alpha-(2-methyladenin-9-yl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+

RXN-19308

EC 2.7.8.26 · RXN-19308 · not reversible · no isoenzyme backup

adenosylcobinamide-GDP adenine ribotide phosphate
Coalpha-[alpha-(adenin-9-yl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+

RXN-19307

EC 2.7.8.26 · RXN-19307 · not reversible · no isoenzyme backup

adenosylcobinamide-GDP 5-methylbenzimidazole ribotide phosphate
Coalpha-[alpha-(5-methylbenzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+

COBALAMIN5PSYN-RXN

EC 2.7.8.26 · COBALAMIN5PSYN-RXN · not reversible · no isoenzyme backup

adenosylcobinamide-GDP alpha-ribazole 5'-phosphate
adenosylcobalamin 5'-phosphate GMP H+

RXN-19305

EC 2.7.8.26 · RXN-19305 · not reversible · no isoenzyme backup

adenosylcobinamide-GDP 5-methoxy-6-methylbenzimidazole ribotide phosphate
Coalpha-[alpha-(5-methoxy-6-methylbenzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+

RXN-25319

EC 2.7.8.26 · RXN-25319 · not reversible · no isoenzyme backup

Consuming chokepoint
adenosylcobinamide-GDP 5-hydroxybenzimidazole ribotide
Coalpha-[alpha-(5-hydroxybenzimidazolyl)]-Cobeta-adenosylcobamide GMP H+

RXN-19302

EC 2.7.8.26 · RXN-19302 · not reversible · no isoenzyme backup

Producing & consuming chokepoint
adenosylcobinamide-GDP benzimidazole ribotide phosphate
Coalpha-[alpha-(benzimidazolyl)]-Cobeta-adenosylcobamide 5'-phosphate GMP H+

Imported from KpATCC43816.sbml · 2026-07-09