Protein profile

VK055_5172

phage portal protein, HK97 family

Genome: KpATCC43816

Gene: AIK83693.1 Structure source: AlphaFold + ColabFold UniProt A0A377ZHY8
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Amino acids 425
Annotations 0
Features 9
PDB binders 0
Druggability 0.85

Overview

Basic information about this protein and its source genome.

Accession
VK055_5172
Assembly
Klebsiella pneumoniae subsp. pneumoniae strain ATCC 43816 KPPR1, complete genome
Gene
AIK83693.1
Status
annotated
Amino acids
425
Structure source
AlphaFold + ColabFold

Target profile

Computed evidence for target prioritization.

Human off-target
No hit
Human identity (%)
0.0
Gut microbiome off-target
hit
Essential (DEG)
N
DEG identity (%)
0.0
Localization
Unknown
ColabFold pLDDT
80.28

Selected Druggability evidence

AlphaFold / UniProt model

Selected Druggability is the FPocket score chosen for ranking using the curated structure priority. The 3D viewer may show a different loaded structure, so its visible pockets can differ.

FPocket 0.85
Structure A0A377ZHY8
Pocket Pocket 27
P2Rank 0.198
Structure A0A377ZHY8
Pocket Pocket 1
ColabFold model
FPocket 0.924 · Pocket 34
P2Rank 0.172 · Pocket 1
Core conservation Accessory gene
Roary accessory
CoreCruncher accessory
Gut microbiome 6 / 4744 genomes with a hit
Normalized 0.001

Sequence

Primary amino-acid sequence viewer.

Functional Annotations

Enzyme classification and Gene Ontology terms linked to this protein.

No GO or EC annotations are currently loaded for this protein.

Sequence Features

Domain/signature hits from InterPro and related databases.

9 records
Show feature table
Start End DB Term Name
401 415 MobiDBLite mobidb-lite consensus disorder prediction
395 425 MobiDBLite mobidb-lite consensus disorder prediction
52 398 NCBIfam TIGR01537 phage portal protein
52 398 InterPro IPR006427 Phage portal protein, HK97
58 332 Gene3D G3DSA:1.20.1270.210 -
78 333 Gene3D G3DSA:3.40.140.120 -
61 392 Pfam PF04860 Phage portal protein
61 392 InterPro IPR006944 Bacteriophage/Gene transfer agent portal protein
223 273 Gene3D G3DSA:3.30.1120.70 -

3D Structure

Selected loaded structure. Experimental PDB entries may cover only a portion of the sequence; predicted models typically cover the full protein.

3D visualization script Full viewer

Loading 3D structure...

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Structural evidence

0 + 2

Experimental PDB entries and predicted models. Click Switch to display a different structure in the viewer.

Entry Method Resolution Chain Coverage Links Status
AlphaFold AF_A0A377ZHY8
AlphaFold — — full sequence — Viewing
ColabFold VK055_5172
ColabFold — — full sequence — Loaded
Pocket details FPocket · P2Rank — toggle visibility and zoom from here, or open full viewer

Pockets (FPOCKET)

Showing top-ranked FPocket candidates by druggability. Druggability is color-coded: high (0.7 or higher), medium (0.4 to 0.69), low (below 0.4).

FPOCKET Sticks Spheres Surfaces Druggability Labels Zoom Positions
27 0.85
4 0.813
26 0.362
18 0.232

Pockets (P2RANK)

Showing top-ranked P2Rank candidates by probability. Probability is color-coded per P2Rank calibration: high (≥ 0.5), medium (0.2 – 0.49), low (< 0.2).

P2RANK Sticks Spheres Surfaces Score Probability Labels Zoom Positions
1 3.69 0.14
2 1.59 0.025
3 1.16 0.009
4 1.13 0.008
5 0.95 0.005