Target Pathogen

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Pockets High Medium Low

Binding pockets · FPocket

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #2

0.981

Likely same site as P2Rank 1 7.2 Å 26 shared residues 84% of smaller site

Unusual size

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Surrounding area

Site 2 FPocket #1

0.231

Likely same site as P2Rank 1 7.0 Å 30 shared residues 97% of smaller site

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Surrounding area

Binding pockets · P2Rank

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.988

Likely same site as FPocket 1 7.0 Å 30 shared residues 97% of smaller site

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Surrounding area

Site 2 P2Rank #2

0.476

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Site 3 P2Rank #3

0.048

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Site 4 P2Rank #4

0.005

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Residue sets

UniProt: Active site:175-175 Nucleophile

UniProt: Binding site:111-115

UniProt: Binding site:139-139

UniProt: Binding site:172-172

UniProt: Binding site:177-177

UniProt: Binding site:217-217

UniProt: Binding site:245-245

UniProt: Binding site:246-247

UniProt: Binding site:268-268

UniProt: Binding site:297-297

UniProt: Binding site:318-319

UniProt: Binding site:62-66

UniProt: Binding site:66-66

UniProt: Binding site:86-86

Binding pockets · FPocket

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #18

0.915

Likely same site as P2Rank 1 6.9 Å 22 shared residues 100% of smaller site

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Surrounding area

Site 2 FPocket #1

0.794

Likely same site as P2Rank 1 3.8 Å 42 shared residues 91% of smaller site

Unusual size

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Binding pockets · P2Rank

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.99

Likely same site as FPocket 1 3.8 Å 42 shared residues 91% of smaller site

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Surrounding area

Site 2 P2Rank #2

0.038

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