Target Pathogen

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Pockets High Medium Low

Binding pockets · FPocket

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #1

0.334

Likely same site as P2Rank 1 1.1 Å 12 shared residues 100% of smaller site

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Surrounding area

Binding pockets · P2Rank

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.344

Likely same site as FPocket 1 1.1 Å 12 shared residues 100% of smaller site

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Surrounding area

Site 2 P2Rank #2

0.343

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Surrounding area

Site 3 P2Rank #3

0.066

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Surrounding area

Site 4 P2Rank #4

0.006

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Surrounding area

Residue sets

UniProt: Active site:342-342 Nucleophile

UniProt: Binding site:424-425

UniProt: Site:360-360 Important for catalytic activity

Binding pockets · FPocket

Druggability: high ≥ 0.7 · medium 0.4–0.69 · low < 0.4

Site 1 FPocket #41

0.734

Likely same site as P2Rank 3 3.5 Å 11 shared residues 100% of smaller site

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Surrounding area

Site 2 FPocket #37

0.293

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Surrounding area

Binding pockets · P2Rank

Probability: high ≥ 0.5 · medium 0.2–0.49 · low < 0.2

Site 1 P2Rank #1

0.151

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Surrounding area

Site 2 P2Rank #2

0.104

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Site 3 P2Rank #3

0.102

Likely same site as FPocket 41 3.5 Å 11 shared residues 100% of smaller site

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Site 4 P2Rank #4

0.079

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Site 5 P2Rank #5

0.057

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Surrounding area

No pocket predictions available for this structure.